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Effet de la radiothérapie sur les cellules souches cancéreuses de cancer du sein : résistance, reprogrammation et traitements
In the past decade, the identification of cancer stem cells (CSCs) has raised new hope for the development of anticancer therapies. Nevertheless, CSC...
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Immunothérapie en onco-urologie
The care of advanced solid cancers has significantly improved with the development of drugs designed to restore the antitumoral immune system. The...
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Antioxidant, anti-inflammatory, and analgesic activities of Citrus reticulata Blanco leaves extracts: An in vivo and in vitro study
Citrus species are cultivated and consumed widely. Citrus have been investigated for their pharmacological activity and human health. Their...
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Congrès de l’association américaine de recherche contre le cancer — AACR 2016
This year, the theme of the American Association for Cancer Research (AACR) conference that held from the 16th to the 20th of April 2016 was...
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Les temps forts de Chicago 2016
The 2016 American Society of Clinical Oncology (ASCO) congress took place in Chicago between 3 and 7 June. Numerous presentations confirmed the...
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Immunothérapie anticancer : les molécules immunomodulatrices en développement clinique
Immune response often fails to control tumor development due to the activation of inefficient lymphocyte or tolerization mechanisms. The goal of...
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Les exosomes en pratique clinique : exemple du cancer bronchique
Exosomes are nanovesicles released by a large number of cells in their physiological and pathological states. They have a specific composition and...
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Congrès Targeted Anticancer Therapies — TAT 2015
The TAT (Targeted Anticancer Therapies) Congress Conference was held in Paris, March 2–4 2015. Once again immunotherapy had the place of honor with...
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Congrès de l’association américaine de recherche contre le cancer — AACR 2015
In this special issue of Oncologie , the French association AERIO (Association d’enseignement et de recherche des internes d’oncologie), constantly...
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Immunothérapie anticancéreuse et cancers digestifs
Despite a known immunosurveillance, Immunotherapy shows low activity in gastro-intestinal (GI) cancer. The most promising strategy could be the use...
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Immunogénicité de la chimiothérapie
Immunogenic cell death is triggered by several cytotoxic agents inducing a release of damage-associated molecular patterns and by dying cells...
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Checkpoint immunologique comme cible thérapeutique
New immunotherapies targeting immune checkpoints can induce prolonged antitumor responses and increased survival. Rather than trying to induce a...
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Place des thérapies moléculaires ciblées dans le traitement des cancers de la tête et du cou
Patients with recurrent or metastatic squamous cell carcinoma of the head and neck have a poor prognosis. After first-line chemotherapy, therapeutics...
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Allongement de l’intervalle QT secondaire aux inhibiteurs des tyrosines-kinases
Tyrosine kinase inhibitors (TKIs) are part of a growing class of treatments, the prescription of which has seen an increase with the identification...
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Carcinomes urothéliaux, formes métastatiques : traitements médicaux d’aujourd’hui et de demain
Urothelial carcinoma remains one of the most common and lethal disease in males. The combination of gemcitabine plus cisplatin with the MVAC regimen...