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1. Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cells

   Retinoic acid (RA)-resistance in breast cancer cells has been associated with irreversible loss of retinoic acid receptor β, RAR β, gene expression....

   Silvia M Sirchia, Anne T Ferguson, ... Nicoletta Sacchi in Oncogene

   Article 16 March 2000
   

2. Differentiation therapy in acute myelogenous leukemia (non-APL)

   Successful treatment of acute promyelocytic leukemia (APL) has identified several novel approaches to induce leukemic cell differentiation and...

   S Waxman in Leukemia

   Article 07 March 2000
   

3. The incidence of acute promyelocytic leukemia appears constant over most of a human lifespan, implying only one rate limiting mutation

   It is believed that most malignancies become more common with increasing age due to the requirement for several mutations to accumulate and...

   M Vickers, G Jackson, P Taylor in Leukemia

   Article 03 April 2000
   

4. Current issues in the management of acute promyelocytic leukemia

   retinoic acid (ATRA), both PML-dependent apoptotic mechanisms and myeloid-specific gene expression programs are reactivated. In the clinic, the...

   J. L. Slack, Michael E. Rusiniak in Annals of Hematology

   Article 01 May 2000

5. Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation

   Metallothionein-I ( MT-I ) gene is silenced by methylation of CpG islands in mouse lymphosarcoma P1798 cells but not in the thymus, the cell type from...

   Sarmila Majumder, Kalpana Ghoshal, ... Samson T Jacob in Oncogene

   Article 18 November 1999
   

6. In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications

   Acute promyelocytic leukemia (APL) is characterized by the expansion of malignant myeloid cells blocked at the promyelocytic stage of hemopoietic...

   Li-Zhen He, Taha Merghoub, Pier Paolo Pandolfi in Oncogene

   Article 20 September 1999
   

7. The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation

   Mutations which disrupt the regulation or expression level of the c- myc gene are among the most common found in human and animal cancers (reviewed in...

   Michael D Cole, Steven B McMahon in Oncogene

   Article 13 May 1999
   

8. Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A

   The PLZF gene was identified by its fusion with the RAR α locus in a therapy resistant form of acute promyelocytic leukemia (APL) associated with the...

   Patricia L Yeyati, Rita Shaknovich, ... Jonathan D Licht in Oncogene

   Article 08 February 1999
   

9. The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT

   Virtually all diffuse large cell lymphomas and a significant fraction of follicular lymphomas contain translocations and/or point mutations in the 5′...

   Khanh D Huynh, Vivian J Bardwell in Oncogene

   Article 12 October 1998

10. Das Bauprinzip der T. muscularis propria des menschlichen Dünndarms als Grundlage für ein biomechanisches Motilitätsmodell

    The structure of the t. muscularis propria of the small intestine was examined in cleared specimen of human cadavers and the scissor like railings...

    M. Henrich, R. Brehler in Research in Experimental Medicine

    Article 01 October 1980