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Neue molekulare Therapien beim nichtkleinzelligen Lungenkarzinom am Beispiel der EGFR/HER1-Inhibition
Background:Lung cancer is one of the most common forms of cancer in western industrialized countries. Patients with advanced non-small cell lung...
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Aktuelle morphologische Diagnostik bösartiger Lungentumoren
The histological classification of lung tumors is based upon the 2004 WHO classification. Small cell lung cancer (SCLC) is primarily treated by means...
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Prognosefaktoren beim Lungenkarzinom
Lung cancer still has a poor prognosis. In order to apply an adequate type and degree of therapy, factors of prognostic relevance are needed. Apart...
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Multimodale Therapie des lokal fortgeschrittenen NSCLC
Patients with locally advanced non-small cell lung cancer (stage IIIB, inoperable stage IIIA) require multimodal therapy. This stage is diagnosed in...
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Erlotinib in der Second-Line-Therapie nichtkleinzelliger Lungenkarzinome
The limited effectiveness of monochemotherapy as second-line therapy for non-small cell lung cancer (NSCLC) requires the development of new...
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Tumorklassifikationen
The correct use of tumor classifications is one of the key elements of adequate oncological treatment. Tumor classifications comprise: localization,...
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Aktuelle Entwicklungen in der Therapie von Knochenmetastasen
In the treatment of bone metastases, interdisciplinary approaches are very important. The goals of therapy are alleviation of pain with improved...
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Apoptose und Tumorregression bei neoadjuvant behandelten lokal fortgeschrittenen nichtkleinzelligen Lungenkarzinomen
Dysregulation of apoptosis is closely associated with malignant cell transformation. On the other hand, apoptosis is induced by chemotherapy or...
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Neoadjuvante Therapie des nichtkleinzelligen Lungenkarzinoms
In the course of a prospective multicenter study, 40 (26 squamous cell and 14 adenocarcinomas) patients with stage IIIA and IIIB non-small cell lung...