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Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs)
Seventeen untreated primary adult glioblastomas were analyzed using immunocytochemistry for the expression of EGF-R, c- neu /erbB2, TGF-α, and...
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Migration of fresh human malignant astrocytoma cells into hydrated gel wafersin vitro
Individual astrocytoma cells expressing a cytoplasmic form of p185 c-neu migrated along basement membrane lined surfaces after xenografing fresh low...
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Determination of a fragment of the c-erbB-2 translational product p185 in serum of breast cancer patients
Concentrations of a fragment of the c- erb B-2 translational product (p185 fragment) were measured in serum of 70 breast cancer patients, 19 healthy...
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The role of erbB2 signal transduction pathways in human breast cancer
The erbB2 receptor is expressed at very high levels in nearly 30% of human breast cancer patients and plays an important role in the transformation...
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Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary
The c- erb B-2 (HER-2/ neu ) protein is a membrane glycoprotein growth factor receptor showing molecular homology with the epidermal growth factor...
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Expression ofHer2/neu oncogene product p185 in correlation to clinicopathological and prognostic factors of gastric carcinoma
The expression of the Her 2/ neu gene product p 185 was retrospectively analyzed in 58 patients with gastric carcinoma. The results were correlated to...
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Amplification and overexpression of the c-erbB-2 protooncogene in human gastric cancer
The c- erb B-2 protooncogene encodes a possible growth factor receptor. This gene has been studied as to whether it can be regarded as a prognostic...
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Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas
Genomic alterations of c- myc (amplification, rearrangements and hypomethylation) were investigated in 30 breast carcinomas and 20 cervix carcinomas....
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Human papillomavirus and c-myc/c-erbB2 in uterine and vulvar lesions
The aim of this study was to investigate papillomavirus (HPV)-DNA in precancer and cancer of the cervix, vulva, and endometrium by in situ/dot blot/...
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c-erbB2 expression in correlation to other biological parameters of breast cancer
On the prognostic value of c- erbB2 -encoded protein p185 in breast cancer there are controversal opinions. With the outlook of an evaluation of the...