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Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice
H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health....
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Avian influenza A (H7N9) virus: from low pathogenic to highly pathogenic
The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry markets. It has caused infections in humans in...
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Mink infection with influenza A viruses: an ignored intermediate host?
Continuously emergence of human infection with avian influenza A virus poses persistent threat to public health, as illustrated in zoonotic H5N1/6...
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A potential Chinese medicine monomer against influenza A virus and influenza B virus: isoquercitrin
BackgroundInfluenza viruses, especially Influenza A virus and Influenza B virus, are respiratory pathogens and can cause seasonal epidemics and...
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A comparison of demographic, epidemiological and clinical characteristics of hospital influenza-related viral pneumonia patients
BackgroundThrough the comparison of the demographic, epidemiological, and clinical characteristics of hospital human influenza (influenza A (H1N1)...
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A systematic review of mechanistic models used to study avian influenza virus transmission and control
The global spread of avian influenza A viruses in domestic birds is causing increasing socioeconomic devastation. Various mechanistic models have...
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Spatial and temporal clusters of avian influenza a (H7N9) virus in humans across five epidemics in mainland China: an epidemiological study of laboratory-confirmed cases
BackgroundAvian influenza A (H7N9) virus was first reported in mainland China in 2013, and alarming in 2016–17 due to the surge across a wide...
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Preparing for pandemics: a systematic review of pandemic influenza clinical management guidelines
BackgroundThe COVID-19 pandemic has highlighted the importance of evidence-based clinical decision-making. Clinical management guidelines (CMGs) may...
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Construction of Influenza Early Warning Model Based on Combinatorial Judgment Classifier: A Case Study of Seasonal Influenza in Hong Kong
ObjectiveThe annual influenza epidemic is a heavy burden on the health care system, and has increasingly become a major public health problem in some...
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Live poultry market closure and avian influenza A (H7N9) infection in cities of China, 2013–2017: an ecological study
BackgroundPrevious studies have proven that the closure of live poultry markets (LPMs) was an effective intervention to reduce human risk of avian...
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RDN for the treatment of influenza in children: a randomized, double-blinded, parallel-controlled clinical trial
BackgroundThe morbidity of influenza in children increased rapidly in decade. Reduning injection (RDN), a small but fine Chinese herbal formula, has...
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Comparison of patients hospitalized with COVID-19, H7N9 and H1N1
BackgroundThere is an urgent need to better understand the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for that...
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Exploring the alternative virulence determinants PB2 S155N and PA S49Y/D347G that promote mammalian adaptation of the H9N2 avian influenza virus in mice
The occurrence of human infections caused by avian H9N2 influenza viruses has raised concerns regarding the potential for human epidemics and...
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Research progress on human infection with avian influenza H7N9
Since the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic...
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G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment
BackgroundGenotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene...
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Associations of telomere length with risk of mortality from influenza and pneumonia in US adults: a prospective cohort study of NHANES 1999–2002
BackgroundDue to the ongoing Coronavirus disease 2019 (COVID-19) pandemic, interest has arisen to realize the relationship between telomere length...
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Emergence of human avian influenza A(H7N9) virus infections in Wenshan City in Southwest China, 2017
BackgroundThe emergence of human infection with avian influenza A(H7N9) virus was reported in Wenshan City, southwestern China in 2017. The study...
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Efficacy of the commercial plant products acting against influenza-a review
BackgroundInfluenza infection always poses a threat to human and animal health. Vaccines and antiviral drugs are recommended to deal with the...
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Derivation and external validation of a simple prediction rule for the development of respiratory failure in hospitalized patients with influenza
BackgroundInfluenza viruses cause seasonal epidemics worldwide with a significant morbimortality burden. Clinical spectrum of Influenza is wide,...
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COVID-19 restrictions limit the circulation of H3N2 canine influenza virus in China
Canine health is consistently affected by the circulation of the H3N2 strain of canine influenza virus (CIV). Prior research has indicated that the...
