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Fibrinogen is an independent preoperative predictor of hospital length of stay among patients undergoing coronary artery bypass grafting
ObjectiveThis study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and hospital length of stay (LOS)...
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Effects of Fibrinogen Concentrate Supplementation on Postoperative Bleeding in Infants Undergoing Complex Cardiac Surgery
The use of allogeneic blood products to restore hemostasis during pediatric cardiac surgery is associated with major risks. Consequently, there has...
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Albumin-to-fibrinogen ratio is an independent predictor of corticosteroid response and prognosis in patients with IgA nephropathy
BackgroundThe objective of this study was to investigate whether the albumin-to-fibrinogen ratio (AFR) can predict corticosteroid response and...
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The role of fibrinogen in traumatic brain injury: from molecular pathological mechanisms to clinical management
Fibrinogen is the substrate of plasma coagulation. It plays an important role in the formation of reticular network, which is crucial to the strength...
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Bronchoscopic lung volume reduction by instillation of fibrinogen and thrombin in COPD patients with homogenous emphysema
BackgroundThe new endobronchial therapy called biological lung volume reduction (BioLVR) involves using a rapid polymerizing sealant to block off the...
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Discovery of Fibrinogen γ-chain as a potential urinary biomarker for renal interstitial fibrosis in IgA nephropathy
BackgroundIgA nephropathy (IgAN) is a major cause of chronic kidney disease (CKD). Renal interstitial fibrosis is a hallmark of CKD progression....
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Higher baseline inflammatory marker levels predict greater cognitive decline in older people with type 2 diabetes: year 10 follow-up of the Edinburgh Type 2 Diabetes Study
Aims/hypothesisWe aimed to determine the longitudinal association of circulating markers of systemic inflammation with subsequent long-term cognitive...
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Novel double-filtration plasmapheresis preserves fibrinogen while removing immunoglobulin-G antibodies before ABO blood type-incompatible kidney transplantation
BackgroundRemoval of anti-blood group antibodies is important for successful ABO-incompatible kidney transplantation (ABOi-KTx). Double-filtration...
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InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations
BackgroundFibrinogen is the first qualified prognostic/predictive biomarker for exacerbations in patients with chronic obstructive pulmonary disease...
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The predictive value of fibrinogen in the occurrence of mild cognitive impairment events in patients with diabetic peripheral neuropathy
BackgroundResearch suggests that fibrinogen (Fib) is related to mild cognitive impairment (MCI) and diabetic peripheral neuropathy (DPN) and the risk...
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Clinical efficacy and safety of tigecycline based on therapeutic drug monitoring for carbapenem-resistant Gram-negative bacterium pneumonia in intensive care units
BackgroundWe investigated the associations between the different doses of tigecycline, its efficacy and safety, and the role of tigecycline...
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Plasma fibrinogen and mortality in patients undergoing peritoneal dialysis: a prospective cohort study
BackgroundPlasma fibrinogen is significantly associated with cardiovascular (CV) events and mortality in the general population. However, the...
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Elevated CSF angiopoietin-2 correlates with blood-brain barrier leakiness and markers of neuronal injury in early Alzheimer’s disease
Breakdown of the neurovascular unit is associated with blood-brain barrier (BBB) leakiness contributing to cognitive decline and disease pathology in...
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Fibrin-Targeting Immunotherapy for Dementia
Blood-brain barrier (BBB) disruption is an early event in the development of Alzheimer’s disease. It precedes extracellular deposition of amyloid-β...
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Our experience of lung resection in patients who decline blood transfusion for religious reasons
ObjectiveSurgical treatment for patients who refuse blood transfusion due to religious beliefs is an important issue related to medical safety. Few...
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Age- and Sex-Different Associations between Cognitive Performance and Inflammatory Biomarkers in Community Dwelling Older Adults: towards Precision Preventive Strategies
BACKGROUNDStudies have demonstrated associations between inflammatory biomarkers and cognitive function in people with dementia or stroke, but little...
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The indicators for early blood transfusion in patients with placental abruption with intrauterine fetal death: a retrospective review
BackgroundPlacental abruption (PA) with intrauterine fetal death (IUFD) is associated with a high risk of postpartum hemorrhage (PPH) resulting from...
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Comparison between the Rotational Thromboelastometry (ROTEM) Delta device against the Cartridge-based Thromboelastography 6s and Quantra in a healthy third trimester pregnant cohort
Rotational Thromboelastometry (ROTEM) Delta has been described in several postpartum hemorrhage algorithms, but this device requires pipetting and...
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Reference intervals of complete blood count and coagulation tests in Vietnamese pregnant women
BackgroundPregnancy has major effects that make hematology parameters outside of normal reference ranges. Therefore, we conducted this study to...
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Characteristics of renal pathology and coagulation function in IgA nephropathy and IgA vasculitis associated nephritis
BackgroundThe objective of this study is to investigate the clinical and pathological differences between patients with IgA nephropathy (IgAN) and...