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Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)
BackgroundBilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...
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Ruxolitinib Cream in Adolescents/Adults with Atopic Dermatitis Meeting Severity Thresholds for Systemic Therapy: Exploratory Analysis of Pooled Results from Two Phase 3 Studies
IntroductionStandard therapy for patients with mild to moderate atopic dermatitis (AD) typically includes topical therapies; however, patients with...
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Cross-linked Sodium Hyaluronate Gel with PLLA-b-PEG Microsphere for Facial Contouring in Chinese: A Retrospective Study
BackgroundIn Asia, the demand for cosmetic facial treatments has surged due to technological advancements, increased social acceptability, and...
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Surgeon variability in repair of hiatal hernia at the time of bariatric surgery
BackgroundHiatal hernia (HH) is estimated to affect between 20 and 50% of patients undergoing bariatric surgery. However, there is no consensus...
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Complications of Superomedial Versus Inferior Pedicle Reduction Mammaplasty: A Systematic Review and Meta-Analysis
BackgroundThe superomedial pedicle reduction mammoplasty has gained popularity and is an important alternative approach for reduction mammoplasty,...
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Differentiating rhythmic high-amplitude delta with superimposed (poly) spikes from extreme delta brushes: limitations of standardized nomenclature and implications for patient management
BackgroundFollowing the standardized nomenclature proposed by the American Clinical Neurophysiology Society (ACNS), rhythmic high-amplitude delta...
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Ethical Considerations and Equipoise in Cancer Surgery
The changing landscape of cancer surgery requires ongoing consideration of ethical issues to ensure patient-centered care and fair access to...
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Optimization of kidney function in cardiac surgery patients with intra-abdominal hypertension: expert opinion
Cardiac surgery-associated acute kidney injury (CSA-AKI) affects up to 42% of cardiac surgery patients. CSA-AKI is multifactorial, with low abdominal...
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Role of gut microbiota and immune cells in metabolic-associated fatty liver disease: clinical impact
In 2020, a revised definition of fatty liver disease associated with metabolic dysfunction (MAFLD) was proposed to replace non-alcoholic fatty liver...
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Discussion of EMA Draft Guideline on Quality and Equivalence of Topical Products Based on Comparison of Approved Mometasone Furoate Drugs
IntroductionToday, the approval for a generic topical product includes the presentation of therapeutic equivalence to the originator based on...
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Clinical relevance of the 3-cm threshold in sigmoid diverticulitis with abscess: consensus or quandary?
PurposeDiverticular abscess is a common manifestation of acute complicated diverticulitis. We aimed to analyze the clinical course of patients with...
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A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion
BackgroundMost patients treated with the standard dosing protocol (SDP) of hepatic arterial infusion (HAI) floxuridine require dose holds and...
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Indocyanine Green Fluorescence-Guided Laparoscopic Anatomical Segmentectomy of Liver Segment 6: Surgical Strategy and Technical Details
BackgroundBecause of the complex anatomy of the right posterior hepatic pedicle, there have been few reports on standardized laparoscopic portal...
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Incisional negative pressure wound therapy (PrevenaTM) vs. conventional post-operative dressing after immediate breast reconstruction: a randomized controlled clinical trial
BackgroundSurgical complications following breast reconstruction remain a significant concern. This study aimed to investigate if incisional negative...
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Living-donor lobar lung transplantation for pulmonary Langerhans cell histiocytosis complicated by extensive thrombi in central pulmonary arteries
BackgroundPulmonary Langerhans cell histiocytosis (PLCH) is a rare disorder characterized by the proliferation of Langerhans cells along the small...
