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Young People’s Barriers and Facilitators of Engagement with Web-Based Mental Health Interventions for Anxiety and Depression: A Qualitative Study
BackgroundThe prevalence of anxiety and depressive symptoms in young people have increased in many countries around the world. Web-based mental...
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Social costs associated with fibromyalgia in Spain
BackgroundFibromyalgia is a chronic rheumatic disease of unknown aetiology, highly disabling and mainly affecting women. The aim of our work is to...
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Cost-Effectiveness of Dupilumab and Oral Janus Kinase Inhibitors for the Treatment of Moderate-to-Severe Atopic Dermatitis in Singapore
BackgroundAtopic dermatitis (AD) affects both adults and children, impacting their quality of life and productivity; however, traditional systemic...
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Incentivizing adherence to pre-exposure prophylaxis for HIV prevention: a randomized pilot trial among male sex workers in Mexico
Low adherence to preventative medications against life-long health conditions is a major contributor to global morbidity and mortality. We...
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Predictors of High Healthcare Cost Among Patients with Generalized Myasthenia Gravis: A Combined Machine Learning and Regression Approach from a US Payer Perspective
BackgroundHigh healthcare costs could arise from unmet needs. This study used random forest (RF) and regression methods to identify predictors of...
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Budget Impact Analysis of Olaparib for the Management of Patients with Homologous Recombination Repair (HRR)-Mutated Castration-Resistant Metastatic Prostate Cancer in Argentina
ObjectivesThe aim of this study was to perform a budget impact analysis (BIA) of introducing olaparib treatment for adult patients with metastatic...
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Use of Cost-Effectiveness Thresholds in Healthcare Public Policy: Progress and Challenges
The article offers a comparative analysis of the influence of cost-effectiveness thresholds in the decision-making processes in financing policies,...
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Untangling the corruption maze: exploring the complexity of corruption in the health sector
BackgroundHealthcare corruption poses a significant threat to individuals, institutions, sectors, and states. Combating corruption is paramount for...
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ENTIMOS: Decision Support Tool Highlights Potential Impact of Non-intravenous Therapies for Multiple Sclerosis on Patient Care via Clinical Scenario Simulation
IntroductionAdministration of intravenous (IV), high-efficacy treatments (HETs) for the treatment of multiple sclerosis (MS) poses a high resourcing...
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How is Value Defined in Molecular Testing in Cancer? A Sco** Review
ObjectiveTo identify how value is defined in studies that focus on the value of molecular testing in cancer and the extent to which broadening the...
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Using a Patient-Centered Multicriteria Decision Analysis to Assess the Value of Multiple Sclerosis Treatments in the US: A Study Protocol
ObjectiveThe engagement of patients and family caregivers in value assessment is pivotal since they provide valuable contributions to assessment...
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Preferences for the Societal Impacts of a Pandemic when it Transitions into an Endemic: A Discrete Choice Experiment
BackgroundThe stage of the pandemic significantly affects people’s preferences for (the societal impacts of) COVID-19 policies. No discrete choice...
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The EQ-5D-3L valuation study for Bermuda: using an on-line EQ-VT protocol
BackgroundIn many countries, methods of economic evaluation and Health Technology Assessment are used to inform healthcare resource allocation...
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The Role of Patient-Reported Outcomes to Measure Treatment Satisfaction in Drug Development
Treatment satisfaction is a person’s rating of his or her treatment experience, including processes and outcomes. It is directly related to treatment...
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Psychometric Properties of the EQ-5D-5L in Patients with Alopecia Areata
BackgroundFor many decision makers in Health Technology Assessment the EQ-5D-5L is the standard measure of health-related quality of life (HRQL)....
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A Multi-dimensional Framework of Valued Output for Primary Care in England
Improving efficiency and productivity are key aspects to ensure that general practices in England can meet the needs of a growing population with...
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Mixture and Non-mixture Cure Models for Health Technology Assessment: What You Need to Know
There is increasing interest in the use of cure modelling to inform health technology assessment (HTA) due to the development of new treatments that...
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Cost-effectiveness of immune checkpoint inhibitors as a first-line therapy for advanced hepatocellular carcinoma: a systematic review
Since 2017, immune checkpoint inhibitors (ICIs) have been available for the treatment of advanced hepatocellular carcinoma (HCC) or unresectable HCC,...
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Discrete Choice Experiments to Elicit Patient Preferences for the Treatment of Major Depressive Disorder: A Systematic Review
BackgroundIndividual preferences for treatment options for major depressive disorder can impact therapeutic decision making, adherence, and...