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A multi-centre longitudinal study analysing multiple sclerosis disease-modifying therapy prescribing patterns during the COVID-19 pandemic
BackgroundThe COVID-19 pandemic raised concern amongst clinicians that disease-modifying therapies (DMT), particularly anti-CD20 monoclonal...
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Alzheimer’s Disease: Combination Therapies and Clinical Trials for Combination Therapy Development
Alzheimer’s disease (AD) is a complex multifaceted disease. Recently approved anti-amyloid monoclonal antibodies slow disease progression by...
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Post-craniotomy leptomeningeal cyst: a new presentation of an old problem
Leptomeningeal cyst (LMC) is a known complication of pediatric head injury but has not been described following a craniotomy other than for...
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Electron Microscopic Map** of Mitochondrial Morphology in the Cochlear Nerve Fibers
To enable nervous system function, neurons are powered in a use-dependent manner by mitochondria undergoing morphological-functional adaptation. In a...
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The Origin Along the Cochlea of Otoacoustic Emissions Evoked by Mid-Frequency Tone Pips
PurposeTone-pip-evoked otoacoustic emissions (PEOAEs) are transient-evoked otoacoustic emissions (OAEs) that are hypothesized to originate from...
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Why do adolescents attempt suicide? Insights from leading ideation-to-action suicide theories: a systematic review
Suicide is a leading cause of death among adolescents, and recent suicide theories have sought to clarify the factors that facilitate the transition...
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Microsurgical management of a ruptured intracranial mycotic aneurysm in infancy
IntroductionDuring infancy, infectious aneurysms are uncommon and potentially fatal lesions with an imminent risk of intracranial hemorrhage...
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The occipital interhemispheric transtentorial approach: historical perspective and evolution over time
PurposeAccess to the pineal region has always represented a fascinating challenge to the neurosurgeons. Almost equally thrilling is the historical...
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Effects of cognitive behavioural therapy and exposure–response prevention on brain activation in obsessive–compulsive disorder patients: systematic review and meta-analysis
Current psychotherapeutic treatments for OCD, while effective, have complex outcomes with mixed efficacy. Previous research has observed baseline...
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Retrospective evaluation of ponticulus posticus prevalence, sella turcica types, and stylohyoid complex calcifications in a group of Turkish population
The aim of this retrospective analysis was to assess the incidence of ponticulus posticus and stylohyoid ligament calcification and to evaluate the...
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Isolated cerebellar stroke in a paediatric patient with typical haemolytic uraemic syndrome: a case report and literature review
Haemolytic Uraemic Syndrome (HUS) is a rare medical condition characterised by microangiopathic haemolytic anaemia, thrombocytopenia, and acute...
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Social context and drug cues modulate inhibitory control in cocaine addiction: involvement of the STN evidenced through functional MRI
Addictions often develop in a social context, although the influence of social factors did not receive much attention in the neuroscience of...
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Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction
Transient receptor potential (TRP) channels play key roles in sensory biology as transducers of various stimuli. Although these ion channels are...
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Pediatric-type diffuse low-grade gliomas
The World Health Organization’s 5th edition classification of Central Nervous System (CNS) tumors differentiates diffuse gliomas into adult and...
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Vaulting further: cranial vault expansion for craniocerebral disproportion without primary craniosynostosis
PurposeTreatment of subjects with refractory idiopathic intracranial hypertension (IIH) or shunted hydrocephalus with chronic shunt complications is...
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VTA glutamatergic projections to the nucleus accumbens suppress psychostimulant-seeking behavior
Converging evidence indicates that both dopamine and glutamate neurotransmission within the nucleus accumbens (NAc) play a role in psychostimulant...
