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Neuroglia in cognitive reserve
The concept of cognitive reserve was born to account for the disjunction between the objective extent of brain damage in pathology and its clinical...
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External validation of clinical risk prediction score for elderly treated with endovascular thrombectomy
Background and aimThe thrombectomy in the elderly prediction score (TERPS) for functional outcome after anterior circulation endovascular therapy...
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Factors underlying the neurofunctional domains of the Addictions Neuroclinical Assessment assessed by a standardized neurocognitive battery
The Addictions Neuroclinical Assessment (ANA) is a neurobiologically-informed framework designed to understand the etiology and heterogeneity of...
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The impact of REM sleep loss on human brain connectivity
Brain function is vulnerable to the consequences of inadequate sleep, an adverse trend that is increasingly prevalent. The REM sleep phase has been...
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Prevalence and 3-month follow-up of cerebrovascular MRI markers in hospitalized COVID-19 patients: the CORONIS study
PurposeTo investigate the prevalence of cerebrovascular MRI markers in unselected patients hospitalized for COVID-19 (Coronavirus disease 2019), we...
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A Long-Term Safety and Tolerability Study of TV-46000 for Subcutaneous Use in Patients with Schizophrenia: A Phase 3, Randomized, Double-Blinded Clinical Trial
BackgroundTV-46000 is a long-acting subcutaneous antipsychotic (LASCA) formulation of risperidone that is approved by the United States Food and Drug...
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Factors associated with a placebo effect in Parkinson’s disease in clinical trials: a meta-analysis
ObjectivesOutcomes of clinical trials of treatment in patients with Parkinson’s disease (PD) may be influenced by placebo effects. The aim of this...
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Coupled changes between ruminating thoughts and resting-state brain networks during the transition into adulthood
Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into...
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Association between previous SARs-CoV-2 infection and new prescription of antidepressant drugs: a case-control study in Friuli Venezia Giulia region, Italy
PurposeA rise in affective and anxiety disorders and in antidepressant (AD) treatment during the COVID-19 pandemic has been extensively described,...
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Approaches to supratentorial brain tumours in children
The differential diagnosis of supratentorial brain tumours in children can be challenging, especially considering the recent changes to the WHO...
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Breakthroughs and challenges for generating brain network-based biomarkers of treatment response in depression
Treatment outcomes widely vary for individuals diagnosed with major depressive disorder, implicating a need for deeper understanding of the...
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The State of Synthetic Cannabinoid Medications for the Treatment of Pain
Synthetic cannabinoids are compounds made in the laboratory to structurally and functionally mimic phytocannabinoids from the Cannabis sativa L . ...
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Distinct synaptic mechanisms drive the behavioral response to acute stress and rapid correction by ketamine
Prevailing hypotheses on the mechanisms of antidepressant action posit that antidepressants directly counteract deficiencies in major...
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Human Olivocochlear Effects: A Statistical Detection Approach Applied to the Cochlear Microphonic Evoked by Swept Tones
The human medial olivocochlear (MOC) reflex was assessed by observing the effects of contralateral acoustic stimulation (CAS) on the cochlear...
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When, Why and How to Re-challenge Clozapine in Schizophrenia Following Myocarditis
Clozapine-induced myocarditis (CIM) is among the most important adverse events limiting the use of clozapine as the most effective treatment for...
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Torticollis as a rare, late complication of VP shunt placement in the pediatric population: a case report
The placement of a ventriculoperitoneal (VP) shunt is a common neurosurgical, pediatric procedure with various, well-documented complications...
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Cannabis-related treatment demand at the eve of German cannabis legalization – a 20-years trend analysis
Post-2000, the prevalence of cannabis consumption has been rising internationally. This paper investigates whether cannabis-related treatment demand...
