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Is depression a global brain disorder with topographic dynamic reorganization?
Major depressive disorder (MDD) is characterized by a multitude of psychopathological symptoms including affective, cognitive, perceptual,...
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A perspective on epigenomic aging processes in the human brain and their plasticity in patients with mental disorders – a systematic review
The debate surrounding nature versus nurture remains a central question in neuroscience, psychology, and in psychiatry, holding implications for both...
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The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking
The parasubthalamic nucleus (PSTN) is activated by refeeding after food deprivation and several PSTN subpopulations have been shown to suppress...
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From movement to motivation: a proposed framework to understand the antidepressant effect of exercise
Depression is the leading cause of disability worldwide, exerting a profound negative impact on quality of life in those who experience it....
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Standardized reporting for Head CT Scans in patients suspected of traumatic brain injury (TBI): An international expert endeavor
Background and purposeTraumatic brain injury (TBI) is a major source of health loss and disability worldwide. Accurate and timely diagnosis of TBI is...
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Neuroimaging and natural language processing-based classification of suicidal thoughts in major depressive disorder
Suicide is a growing public health problem around the world. The most important risk factor for suicide is underlying psychiatric illness, especially...
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Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents
The mechanisms contributing to alcohol use disorder (AUD) are complex and the orexigenic peptide ghrelin, which enhances alcohol reward, is implied...
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Real-world data of in-hospital administration of alglucosidase alfa in French patients with Pompe disease: results from the National Claims Database
IntroductionPompe disease is caused by a rare biallelic mutation in the GAA gene resulting in acid α-glucosidase deficiency and glycogen...
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Vitamin D, chronic pain, and depression: linear and non-linear Mendelian randomization analyses
Vitamin D deficiency has been linked to various chronic pain conditions. However, randomized trials of vitamin D supplementation have had mixed...
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Systematic review-based guideline “Parkinson’s disease” of the German Society of Neurology: diagnostic use of transcranial sonography
Background and objectiveTranscranial brain parenchyma sonography (TCS) has been recommended as a tool for the early and differential diagnosis of...
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A systematic review of structural and functional magnetic resonance imaging studies on the neurobiology of depressive symptoms in schizophrenia spectrum disorders
Depressive symptoms in Schizophrenia Spectrum Disorders (SSDs) negatively impact suicidality, prognosis, and quality of life. Despite this,...
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Criteria for stop** high-flow nasal oxygen for acute hypoxemic respiratory failure: a systematic review of randomized controlled trials
High-flow nasal cannula (HFNC) has been widely promoted during the COVID-19 pandemic to circumvent invasive mechanical ventilation. While there are...
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Epigenetic signals associated with delirium replicated across four independent cohorts
Delirium is risky and indicates poor outcomes for patients. Therefore, it is crucial to create an effective delirium detection method. However, the...
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Reduced speech coherence in psychosis-related social media forum posts
The extraction of linguistic markers from social media posts, which are indicative of the onset and course of mental disorders, offers great...
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Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis
BackgroundAquaporin-4 (AQP4) antibody-associated neuromyelitis optica spectrum disorder (NMOSD) is an antibody-mediated inflammatory disease of the...
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Widespread haemorrhages in infants post-shunting (WHIPS): clinical features, risk factors and neuroimaging characteristics of a rare and under-recognised phenomenon
PurposeInfants undergoing CSF shunting procedures face a rare complication which we propose to rename “Widespread Haemorrhages in Infants...
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Tenecteplase versus alteplase before stroke thrombectomy: outcomes after system-wide transitions in Pennsylvania
IntroductionUnited States stroke systems are increasingly transitioning from alteplase (TPA) to tenecteplase (TNK). Real-world data on the safety and...
