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Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases
Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...
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Patient attitudes and experiences towards exercise during oncological treatment. A qualitative systematic review
PurposeExercise and physical activity (PA) during oncological treatment have many benefits. However, PA levels and adherence are often low. This...
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Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus
AimsDipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...
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An elderly case of paraneoplastic anti-NMDA receptor encephalitis associated with large cell neuroendocrine carcinoma of the lung
BackgroundRecent studies have suggested that N-methyl-D-aspartate (NMDA) receptors are involved in the cell proliferation in several tumors. However,...
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Use of diabetes technology in children
Children with type 1 diabetes and their caregivers face numerous challenges navigating the unpredictability of this complex disease. Although the...
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Decreased levels of PTCSC3 promote the deterioration of prostate cancer and affect the prognostic outcome of patients through sponge miR-182-5p
BackgroundProstate cancer, characterized by its insidious onset and short overall survival, and has seen a rise in incidence over recent decades....
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Development and validation of AI-derived segmentation of four-chamber cine cardiac magnetic resonance
BackgroundCardiac magnetic resonance (CMR) in the four-chamber plane offers comprehensive insight into the volumetrics of the heart. We aimed to...
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Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway
BackgroundHyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...
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Changes in femoral anteversion after intramedullary nailing for pediatric femoral shaft fracture: a multicenter study
BackgroundThe rotational change after using a flexible intramedullary (IM) nail for femoral shaft fractures has been a concern for many surgeons....
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Mucinous tubular and spindle renal cell carcinoma revealed by a trauma of the kidney: a case report
BackgroundMucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health...
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Association of resection margin distance with anastomotic recurrence in stage I-III colon cancer: data from the National Colorectal Cancer Cohort (NCRCC) study in China
PurposeFew studies have focused on anastomotic recurrence (AR) in colon cancer. This study aimed to clarify the association of resection margin...
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Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography
Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be...
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Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Purpose of ReviewCalcitonin gene-related peptide (CGRP) pathway modulators, such as atogepant, represent a novel therapeutic option for the treatment...
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Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)
BackgroundBilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...
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Screening for diabetic retinopathy with artificial intelligence: a real world evaluation
AimPeriodic screening for diabetic retinopathy (DR) is effective for preventing blindness. Artificial intelligence (AI) systems could be useful for...
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Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration
BackgroundHuman intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is...
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Mammographic features differ with body composition in women with breast cancer
ObjectivesThere are several breast cancer (BC) risk factors—many related to body composition, hormonal status, and fertility patterns. However, it is...
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Zero-echo time MRI: an alternative method for the diagnosis of urinary stones in children
ObjectivesTo evaluate the potential of zero-echo time-magnetic resonance imaging (ZTE-MRI) in the assessment of urolithiasis and compare ZTE-MRI with...
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Radiomics predict the WHO/ISUP nuclear grade and survival in clear cell renal cell carcinoma
ObjectivesThis study aimed to assess the predictive value of radiomics derived from intratumoral and peritumoral regions and to develop a radiomics...
