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An elderly case of paraneoplastic anti-NMDA receptor encephalitis associated with large cell neuroendocrine carcinoma of the lung
BackgroundRecent studies have suggested that N-methyl-D-aspartate (NMDA) receptors are involved in the cell proliferation in several tumors. However,...
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Trace of delirium after robotic lower abdominal tumor resection at different end-tidal carbon dioxide: a RCT trial
BackgroundPostoperative delirium (POD) often occurs in oncology patients, further increasing the medical and financial burden. Robotic technology in...
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Prognostic value of serial (1,3)-β-d-glucan measurements in ICU patients with invasive candidiasis
BackgroundTo determine whether a decrease in serum (1,3)-β- d -glucan (BDG) was associated with reduced mortality and to investigate the performance...
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3D C-arm navigated suture button implantation for AC joint dislocations - the pilot study
PurposeThe surgical treatment of acute traumatic AC joint dislocations is still a subject of scientific debate in the literature. The...
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The role of upper airway ultrasonography in tracheal necrosis diagnosis: a case report
BackgroundTracheal necrosis post endotracheal intubation is a rare life-threatening disease that can compromise airway patency. We demonstrated a...
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Transcriptomic Expression of T2-Inflammation Genes in Peripheral Blood Mononuclear Cells and Longitudinal Clinical Outcomes in Asthma: Insights from the COREA Study
BackgroundGene expression can provide distinct information compared to clinical biomarkers in the context of longitudinal clinical outcomes in asthma...
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Good outcome with conservative treatment of delayed spinal epidural hematoma following combined spinal-epidural anesthesia: a rare case report
BackgroundDelayed spinal epidural hematoma (SEH) following central neuraxial block (CNB) is a rare but serious complication. The underlying causes of...
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Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Purpose of ReviewCalcitonin gene-related peptide (CGRP) pathway modulators, such as atogepant, represent a novel therapeutic option for the treatment...
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Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods
PurposeContinuous positive airway pressure (CPAP) is the primary therapy for obstructive sleep apnea (OSA); however the effectiveness of CPAP remains...
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Longitudinal lung function trajectories in response to azithromycin therapy for chronic lung disease in children with HIV infection: a secondary analysis of the BREATHE trial
BackgroundChronic lung disease (CLD) is common among children with HIV (CWH) including in those taking antiretroviral therapy (ART). Azithromycin has...
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Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)
BackgroundCritical-illness survivors may experience post-traumatic stress disorder (PTSD) and quality-of-life impairments. Resilience may protect...
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Differentiating rhythmic high-amplitude delta with superimposed (poly) spikes from extreme delta brushes: limitations of standardized nomenclature and implications for patient management
BackgroundFollowing the standardized nomenclature proposed by the American Clinical Neurophysiology Society (ACNS), rhythmic high-amplitude delta...
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BART, the new robotic assistant: big data, artificial intelligence, robotics, and telemedicine integration for an ICU 4.0
We are in the era of Health 4.0 when novel technologies are providing tools capable of improving the quality and safety of the services provided. Our...
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The integrin receptor beta7 subunit mediates airway remodeling and hyperresponsiveness in allergen exposed mice
BackgroundFibroblast differentiation to a myofibroblast phenotype is a feature of airway remodeling in asthma. Lung fibroblasts express the integrin...
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Metagenomic next-generation sequencing promotes diagnosis and treatment of Pneumocystis jirovecii pneumonia in non-HIV infected children: a retrospective study
BackgroundMetagenomic next-generation sequencing (mNGS) excels in diagnosis of infection pathogens. We aimed to evaluate the performance of mNGS for...
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Optimization of kidney function in cardiac surgery patients with intra-abdominal hypertension: expert opinion
Cardiac surgery-associated acute kidney injury (CSA-AKI) affects up to 42% of cardiac surgery patients. CSA-AKI is multifactorial, with low abdominal...
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Performing polysomnography in pre-school aged children: challenging parts of the procedure and risk factors for lead intolerance
PurposePediatric sleep apnea begins in toddlerhood when sleep is vital for neurocognitive development and rapid somatic growth. As polysomnography...
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The utility of various predictive equations in patients with severe Obstructive Sleep Apnea: a clinical practice viewpoint in settings with limited resources
BackgroundThe continuous positive airway pressure (CPAP) needed for the treatment of obstructive sleep apnea (OSA) can be determined after a manual...