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Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice
PurposeFibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...
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Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme
The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT...
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Extra-abdominal trocar and instrument detection for enhanced surgical workflow understanding
PurposeVideo-based intra-abdominal instrument tracking for laparoscopic surgeries is a common research area. However, the tracking can only be done...
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Advancing medical imaging: detecting polypharmacy and adverse drug effects with Graph Convolutional Networks (GCN)
Polypharmacy involves an individual using many medications at the same time and is a frequent healthcare technique used to treat complex medical...
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Comparison of the dosimetry of scandium-43 and scandium-44 patient organ doses in relation to commonly used gallium-68 for imaging neuroendocrine tumours
BackgroundSeveral research groups have explored the potential of scandium radionuclides for theragnostic applications due to their longer half-lives...
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Efficacy and safety of rechallenge [177Lu]Lu-PSMA-617 RLT after initial partial remission in patients with mCRPC: evaluation of a prospective registry (REALITY study)
AimRechallenge of [ 177 Lu]Lu-PSMA-617 radioligand therapy (RLT) was proposed for patients who initially responded to PSMA-RLT experiencing partial...
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Evidence for Intermittent Theta Burst Transcranial Magnetic Stimulation for Dysphagia after Stroke: A Systematic Review and Meta-analysis
Dysphagia is the most common serious complication after stroke, with an incidence of about 37–78%, which seriously affects the independence of...
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Exploring the relationship between epicardial fat and coronary plaque burden and characteristics: insights from cardiac ct imaging
Epicardial adipose tissue (EAT) may enhance the risk of coronary artery disease (CAD). We investigated the relationship between EAT density (a maker...
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MHC-I and PD-L1 Expression is Associated with Decreased Tumor Outgrowth and is Radiotherapy-inducible in the Murine Head and Neck Squamous Cell Carcinoma Model MOC1
IntroductionCombined radiotherapy and immune checkpoint inhibition is a potential treatment option for head and neck squamous cell carcinoma (HNSCC)....
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Comparison of Complications in Patients with Ductal Cholangiocarcinoma (CCC) and Patients with Colorectal Liver Metastases (CRLMs) After Portal Vein Embolization (PVE): A Matched Cohort Study
PurposeTo compare complications in patients with cholangiocarcinoma (CCC) and patients with colorectal liver metastases (CRLMs) after portal vein...
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Present and future of whole-body MRI in metastatic disease and myeloma: how and why you will do it
Metastatic disease and myeloma present unique diagnostic challenges due to their multifocal nature. Accurate detection and staging are critical for...
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Pareto optimization of SPECT acquisition and reconstruction settings for 177Lu activity quantification
BackgroundThe aim was to investigate the noise and bias properties of quantitative 177 Lu-SPECT with respect to the number of projection angles, and...
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Evaluation of a novel 177Lu-labelled therapeutic Affibody molecule with a deimmunized ABD domain and improved biodistribution profile
PurposeFusion of Affibody molecules with an albumin-binding domain (ABD) provides targeting agents, which are suitable for radionuclide therapy. To...
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Complicated Inguinal Hernia Incidentally Detected on a Radiolabelled Autologous White Blood Cell Scan
A 73-year-old male with left hip prosthesis infection performed a 99m Tc HMPAO–labelled autologous WBC (WBC) scan to evaluate the response to...
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Preclinical evaluation of CXCR4 peptides for targeted radionuclide therapy in glioblastoma
BackgroundGlioblastoma (GBM), is the most fatal form of brain cancer, with a high tendency for recurrence despite combined treatments including...
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Global public concern of childhood and adolescence suicide: a new perspective and new strategies for suicide prevention in the post-pandemic era
BackgroundSuicide is the second leading cause of death in young people worldwide and is responsible for about 52,000 deaths annually in children and...