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Comparison of inflammatory markers in low-pressure pneumoperitoneum with deep neuromuscular block versus standard pressure pneumoperitoneum among patients undergoing laparoscopic cholecystectomy for gallstone disease: a randomized control trial
BackgroundLow-pressure pneumoperitoneum (LPP) is an attempt to improve laparoscopic surgery. Lower pressure causes lesser inflammation and better...
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Treatment challenges and outcomes of older patients with acute myeloid leukemia from India
Globally, overall survival (OS) of older patients with AML continues to be suboptimal with very little data from India. In a multicenter registry...
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Cardiac safety of ribociclib evaluated with 24-hour rhythm Holter electrocardiogram
ObjectiveWe aimed to evaluate cardiac safety profile of ribociclib with 24-h rhythm Holter ECG.
Material and methodForty-two female metastatic...
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Total-body dynamic PET/CT imaging reveals kinetic distribution of [13N]NH3 in normal organs
PurposeTo systematically investigate kinetic metrics and metabolic trap** of [ 13 N]NH 3 in organs.
MethodsEleven participants performed total-body [
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Transcobalamin deficiency — a rare genetic defect in transportation of cobalamin; case report
BackgroundVitamin B12 is primarily transported from plasma to cells by Transcobalamin. Deficiency of Transcobalamin is a rare autosomal recessive...
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Nodal Surgery for Patients ≥ 70 Undergoing Mastectomy for DCIS? Choose Wisely
BackgroundRoutine sentinel lymphadenectomy (SLNB) for early-stage HR+/HER2- breast cancer in women ≥70 is discouraged by Choosing Wisely, but whether...
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Construction and validation of a nomogram for predicting survival in elderly patients with severe acute pancreatitis: a retrospective study from a tertiary center
PurposeThere is a lack of adequate models specifically designed for elderly patients with severe acute pancreatitis (SAP) to predict the risk of...
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The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD)-related advanced fibrosis and cirrhosis in the United States population utilizing AGILE 3 + and AGILE 4 scores: analysis of the NHANES 2017–2018 cycle
BackgroundStudies attempted to estimate MASLD-related advanced fibrosis (AF) and cirrhosis (MC) prevalence utilized tests with low positive...
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Prognosis based on postoperative PSA levels and treatment in prostate cancer with lymph node involvement
BackgroundThe therapeutic role of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) for prostate cancer is not established. In...
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Exploring the integration of dentistry within a multidisciplinary palliative care team: does bedside dental care improve quality of life and symptom burden in inpatient palliative care patients?
BackgroundDespite the significant impact of oral problems on the quality of life of palliative care patients, comprehensive studies are lacking. This...
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The Current Landscape of Clinical Trials for Immunotherapy in Pancreatic Cancer: A State-of-the-Art Review
BackgroundPancreatic cancer remains a lethal malignancy with a 5-year survival rate below 6% and about 500,000 deaths annually worldwide. Pancreatic...
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The role of multimodality imaging in the selection and management of patients treated with cytoreductive surgery and HIPEC
Cytoreductive surgery (CRS) with or without hyperthermic intraperitoneal chemotherapy (HIPEC) is the mainstay of potentially curative surgical...
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Diagnostic accuracy and reliability of CT-based Node-RADS for colon cancer
ObjectiveThe Node-RADS classification was recently published as a classification system to better characterize lymph nodes in oncological imaging....
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Early and late assessment of renal allograft dysfunction using intravoxel incoherent motion (IVIM) and diffusion-weighted imaging (DWI): a prospective study
PurposeTo evaluate the ability of the Intravoxel Incoherent Motion (IVIM) and monoexponentially ADC in renal allograft function in the early and late...
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Quality of Life Evaluation in Patients with Follicular Cell Lymphoma: A Real-World Study in Europe and the United States
IntroductionFollicular lymphoma (FL) is an indolent subtype of non-Hodgkin's lymphoma (NHL), characterized by a long natural course of...
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Contemporary Axillary Surgical Management in Patients with Pathologically Node Positive Disease After Neoadjuvant Chemotherapy: A Survey of Members of the American Society of Breast Surgeons
BackgroundAxillary lymph node dissection (ALND) is increasingly omitted for breast cancer patients with pathologic nodal disease after neoadjuvant...