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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis
BackgroundPre-frailty is associated with increased healthcare utilization. Over the past decade, public health interventions such as community-based...
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Pediatric shunt failure in a resource limited Lower-Middle Income Country (LMIC) institution in La Paz, Bolivia
BackgroundShunt failure is an undesirable but common occurrence following neurosurgical shunting for pediatric hydrocephalus. Little is known about...
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Ultrasound Urodynamics: A Review of Ultrasound Imaging Techniques for Enhanced Bladder Functional Diagnostics
Purpose of ReviewInvasive urodynamics are currently used to diagnose disorders of bladder function. However, due to patient discomfort as well as...
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Elevated serum kynurenic acid in individuals with first-episode psychosis and insufficient response to antipsychotics
The tryptophan-metabolizing kynurenine pathway (KP) can be activated by enhanced inflammatory responses and has been implicated in the...
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Step** towards health: a sco** review of square-step** exercise protocols and outcomes in older adults
BackgroundSquare-Step** Exercise (SSE) is a type of physical-cognitive exercise. Such exercise has been used as an exercise approach in different...
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Decreased DTI-ALPS index in delirium: a preliminary MRI study
PurposeDelirium is linked to brain abnormalities, yet the role of the glymphatic system is not well understood. This study aims to examine...
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Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases
Proteolytic cell surface release (‘shedding’) of the prion protein (PrP), a broadly expressed GPI-anchored glycoprotein, by the metalloprotease...
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The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study
BackgroundAlthough gabapentin has been increasingly prescribed to older adults, the relation between gabapentin initiation and longer-term...
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Neural correlates of depression-related smartphone language use in adolescents
Magnetic resonance imaging has provided pathophysiological insights into adolescent depression but is a relatively inaccessible technology....
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Dissecting the vascular-cognitive nexus: energetic vs. conventional hemodynamic parameters
Blood pressure or flow measurements have been associated with vascular health and cognitive function. We proposed that energetic hemodynamic...
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Defining tumor growth in vestibular schwannomas: a volumetric inter-observer variability study in contrast-enhanced T1-weighted MRI
PurposeFor patients with vestibular schwannomas (VS), a conservative observational approach is increasingly used. Therefore, the need for accurate...
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Self-expanding intracranial drug-eluting stent system in patients with symptomatic intracranial atherosclerotic stenosis: initial experience and midterm angiographic follow-up
BackgroundSymptomatic intracranial atherosclerotic stenosis (ICAS) is a major cause of ischemic stroke worldwide. In patients undergoing endovascular...
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Can geroscience be translated into healthcare?
As an introduction to this special issue on geroscience, the present work focuses on the complexity of disentangling biomolecular mechanisms of aging...
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Applying Kumpfer’s resilience framework to understand the social adaptation process of the trailing parents in China
BackgroundTrailing parents, a distinct group emerging from China’s rapid social change and urbanization, are experiencing migration in old age,...
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Hypothetical Interventions on Cardiovascular Health Metrics for Abnormal Cognitive Aging: An Application of the Parametric g-formula in the CLHLS Cohort Study with 12 Years Follow-Up
BackgroundAbnormal cognitive aging is closely related to dementia.
ObjectivesThis study aimed to estimate the effect of cardiovascular health (CVH)...
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Impairment of the GABAergic system in the anterior insular cortex of heroin-addicted males
Opioid addiction is a global problem, causing the greatest health burden among drug use disorders, with opioid overdose deaths top** the statistics...
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Impact of post-thrombectomy isolated subarachnoid hemorrhage on neurological outcomes in patients with anterior ischemic stroke – a retrospective single-center observational study
PurposeWe aimed to investigate the impact of post-thrombectomy isolated subarachnoid hemorrhage (i-SAH) and other types of intracranial hemorrhage...
