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Use of Cefiderocol in Adult Patients: Descriptive Analysis from a Prospective, Multicenter, Cohort Study
IntroductionCefiderocol is a siderophore cephalosporin showing activity against various carbapenem-resistant Gram-negative bacteria (CR-GNB). No data...
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The value of deep learning-based X-ray techniques in detecting and classifying K-L grades of knee osteoarthritis: a systematic review and meta-analysis
ObjectivesKnee osteoarthritis (KOA), a prevalent degenerative joint disease, is primarily diagnosed through X-ray imaging. The Kellgren-Lawrence...
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Longitudinal lung function trajectories in response to azithromycin therapy for chronic lung disease in children with HIV infection: a secondary analysis of the BREATHE trial
BackgroundChronic lung disease (CLD) is common among children with HIV (CWH) including in those taking antiretroviral therapy (ART). Azithromycin has...
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Mammographic features differ with body composition in women with breast cancer
ObjectivesThere are several breast cancer (BC) risk factors—many related to body composition, hormonal status, and fertility patterns. However, it is...
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Discussion of EMA Draft Guideline on Quality and Equivalence of Topical Products Based on Comparison of Approved Mometasone Furoate Drugs
IntroductionToday, the approval for a generic topical product includes the presentation of therapeutic equivalence to the originator based on...
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Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis
ObjectivesTo identify factors influencing the diagnostic performance of the quantitative imaging biomarkers ADC and ADCratio in prostate cancer (PCa)...
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Clinical Application of Different Doses of Hydromorphone Slow-Release Analgesia in Lumbar Fusion in Elderly Patients
IntroductionThe aim of this study is to examine the analgesic efficacy of varying doses of hydromorphone hydrochloride in conjunction with absorbable...
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Gastric bezoars secondary to mixed infection with Sarcina ventriculi and G + bacilli: a case report
Sarcina ventriculi is a bacterium with a specific histological morphology and infection can present with symptoms such as abdominal pain, nausea,...
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Unlocking the therapeutic potential of Nigella sativa extract: phytochemical analysis and revealing antimicrobial and antioxidant marvels
The growing global threat of antimicrobial resistance endangers both human and animal life, necessitating the urgent discovery of novel antimicrobial...
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Dapagliflozin, inflammation and left ventricular remodelling in patients with type 2 diabetes and left ventricular hypertrophy
Background and AimsSodium-glucose co-transporter 2 (SGLT2) inhibitors have beneficial effects in heart failure (HF), including reverse remodelling,...
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Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances
All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and...
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Analyzing the molecular mechanism of Scutellaria Radix in the treatment of sepsis using RNA sequencing
BackgroundSepsis is a life-threatening organ dysfunction, which seriously threatens human health. The clinical and experimental results have...
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Sonological predictors of complications of percutaneous renal biopsy—a prospective observational study
AbstractPercutaneous renal biopsy, although essential for renal disease diagnosis, is associated with a number of post-biopsy complications ranging...
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Performing polysomnography in pre-school aged children: challenging parts of the procedure and risk factors for lead intolerance
PurposePediatric sleep apnea begins in toddlerhood when sleep is vital for neurocognitive development and rapid somatic growth. As polysomnography...
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The Role of Widefield Optical Coherence Tomography Angiography in Assessing the Severity of Diabetic Retinopathy
IntroductionPhysicians need an accurate understanding of diabetic retinopathy (DR) severity to optimally manage patients. The aim of this prospective...
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Review of Malaysian medicinal plants with potential wound healing activity
Wound is defined as the damage to biological tissues including skin, mucous membranes and organ tissues. The acute wound heals in less than 4 weeks...
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Downstream Emergency Department and Hospital Utilization Comparably Low Following In-Person Versus Telemedicine Primary Care for High-Risk Conditions
BackgroundTelemedicine use expanded greatly during the COVID-19 pandemic. More data is needed to understand how this shift may impact other venues of...
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