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“Don’t talk to me like I am an illness”: exploring patients’ needs using the communication passport in an eating disorder service
PurposeSocial challenges are common in patients with eating disorders (ED). The presence of autistic characteristics often exacerbates social...
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Efficacy and Safety of Atogepant for Preventing Chronic and Episodic Migraines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Purpose of ReviewCalcitonin gene-related peptide (CGRP) pathway modulators, such as atogepant, represent a novel therapeutic option for the treatment...
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De-escalation and Discontinuation of Disease-Modifying Therapies in Multiple Sclerosis
Purpose of ReviewLong-term use of multiple sclerosis (MS) disease-modifying therapies (DMTs) is standard practice to prevent accumulation of...
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Bow hunter’s syndrome due to an anomalous right vertebral artery origin and contralateral absence: a case report and literature review
BackgroundBow Hunter’s syndrome (BHS), also known as rotational vertebral artery occlusion (RVAO), is a rare condition characterized by dynamic...
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Initial Validation of the Self Experiences Questionnaire-2 in People with Chronic Pain
PurposeThe struggle with sense of self has a fundamental impact on health and wellbeing in people with chronic pain. Acceptance and Commitment...
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Doing more with less: surgical results of pediatric posterior fossa tumors from a single center in Latin America
ObjectiveWe aim to report the epidemiology, surgical outcomes, and survival rates of pediatric patients with posterior fossa tumors in a large...
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Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods
PurposeContinuous positive airway pressure (CPAP) is the primary therapy for obstructive sleep apnea (OSA); however the effectiveness of CPAP remains...
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Sleep profiles of different psychiatric traits
Disturbed sleep comes in many forms. While the key role of sleep in mental health is undisputed, our understanding of the type of slee** problems...
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DNA methylation patterns in the frontal lobe white matter of multiple system atrophy, Parkinson’s disease, and progressive supranuclear palsy: a cross-comparative investigation
Multiple system atrophy (MSA) is a rare neurodegenerative disease characterized by neuronal loss and gliosis, with oligodendroglial cytoplasmic...
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Super T2-FLAIR mismatch sign: a prognostic imaging biomarker for non-enhancing astrocytoma, IDH-mutant
PurposeThe T2-FLAIR mismatch sign is a highly specific diagnostic imaging biomarker for astrocytoma, IDH-mutant. However, a definitive prognostic...
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Improving Quality of Care for Status Epilepticus: Putting Protocols into Practice
Purpose of ReviewTimely treatment of status epilepticus (SE) improves outcomes, however gaps between recommended and implemented care are common....
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Performing polysomnography in pre-school aged children: challenging parts of the procedure and risk factors for lead intolerance
PurposePediatric sleep apnea begins in toddlerhood when sleep is vital for neurocognitive development and rapid somatic growth. As polysomnography...
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Increased body mass index (BMI) associated with late epilepsy onset in patients with temporal encephaloceles: a systematic review and analysis of individual patient data
ObjectiveThis study investigates the association of Body Mass Index (BMI) and age of epilepsy onset, in patients with epilepsy associated with...
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The spectrum of anti-GQ1B antibody syndrome: beyond Miller Fisher syndrome and Bickerstaff brainstem encephalitis
IntroductionSince the initial identification of Miller Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis (BBE),significant milestones have...
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Complex intracranial aneurysms: a DELPHI study to define associated characteristics
PurposeIntracranial aneurysms present significant health risks, as their rupture leads to subarachnoid haemorrhage, which in turn has high morbidity...
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Universal Prevention of Dementia in Italy: A Document Analysis of the 21 Italian Regional Prevention Plans
BackgroundUp to 40% of dementia cases are theoretically avoidable and population-level interventions (i.e., universal prevention) are a key component...