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Risk of teratogenicity in continued pregnancy after gestational exposure to mifepristone and/or misoprostol: a systematic review and meta-analysis
PurposeThis meta-analysis aimed to comprehensively assess the teratogenic risk to offspring associated with continuing pregnancy after administering...
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Androgen transition and management of hereditary angioedema long-term prophylaxis in real life: a single-center case series
BackgroundHereditary angioedema (HAE) is a rare and potentially life-threatening disease that manifests clinically as recurrent episodes of swelling...
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Involvement of Kindlin-1 in cutaneous squamous cell carcinoma
Kindler syndrome (KS) is a rare genodermatosis resulting from loss-of-function mutations in FERMT1 , the gene that encodes Kindlin-1. KS patients have...
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A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori
Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...
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Trophectoderm grade as a predictor of beta human-chorionic gonadotropin rise in early pregnancy
PurposeTo evaluate the association, if any, between the grade of the trophectoderm (TE) and the rate at which β-human-chorionic gonadotropin (β-HCG)...
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Distribution pattern of the celiac, cranial mesenteric, and caudal mesenteric arteries to the gastrointestinal tract in the common marmoset (Callithrix jacchus)
Gastrointestinal diseases pose problems to captive common marmosets. Therefore, knowledge of the anatomy of the arterial supply to the...
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Patient perceptions of remote patient monitoring program for hypertensive disorders of pregnancy
PurposeThe utilization of remote patient monitoring (RPM) with home blood pressure monitoring has shown improvement in blood pressure control and...
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Recurrent pelvic organ prolapse after hysterectomy; a 10-year national follow-up study
PurposeHysterectomy may be a risk factor for pelvic organ prolapse (POP). We assessed the risk of recurrent POP (operations and visits) after...
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Maternal and perinatal infectious morbidity in term prelabor rupture of membrane according to two induction of labor protocols
PurposeThe optimal labor-induction protocol in women with prelabor rupture of membranes (PROM) is unknown. Whether the management of women with a...
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TREK-1 channel as a therapeutic target for dexmedetomidine-mediated neuroprotection in cerebral ischemia
Our objective is to explore the protective effect of Dexmedetomidine on brain apoptosis and its mechanism through TREK-1 pathway. Forty male...
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Spinocerebellar ataxia type 27B (SCA27B) in India: insights from a large cohort study suggest ancient origin
BackgroundThe ethnic diversity of India provides a unique opportunity to study the history of the origin of mutations of genetic disorders....
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Fertility-sparing strategy in a rare case of highly malignant Dicer-1-associated sarcoma of the cervix
IntroductionWe present the rare case of an 18-year-old patient with a Dicer-1 mutation-associated sarcoma of the cervix uteri.
CaseThe patient...
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Epidemiology, economic, and humanistic burden of hereditary angioedema: a systematic review
BackgroundThis systematic study aims to assess the global epidemiologic, economic, and humanistic burden of illness associated with all types of...
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Imatinib Mesylate Causes Potential Cardiac Dysfunction in Patients With Chronic Myeloid Leukemia: the Results of a Case–control Study
Unlike second-generation tyrosine kinase inhibitors, effects of imatinib on the cardiovascular (CV) system are debatable. The current case–control...