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Biomarkers of tissue remodelling are elevated in serum of COVID-19 patients who develop interstitial lung disease - an exploratory biomarker study
BackgroundCoronavirus disease 2019 (COVID-19) is a viral pneumonia that can result in serious respiratory illness. It is associated with extensive...
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Regorafenib plus FOLFIRINOX as first-line treatment for patients with RAS-mutant metastatic colorectal cancer (FOLFIRINOX-R trial): a dose-escalation study
PurposeThe combination of bevacizumab and FOLFIRINOX is used in patients with RAS-mutant metastatic colorectal cancer (RASm-mCRC). Regorafenib, an...
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Assessment of the Prognostic Importance of The Revised International Staging System Based on Plasmacytoma Presentation in Recently Diagnosed Patients with Multiple Myeloma
The rapid development of fluorescence in situ hybridization (FISH) karyoty** led to the discovery of the significant prognostic impact of certain...
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Apneic Oxygenation: A Narrative Review
Purpose of ReviewThe purpose of this review is to explore the underlying physiology and clinical applications of apneic oxygenation, a technique...
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B Lineage Acute Lymphoblastic Leukemia with concurrent IGH and EPOR rearrangements – An Entity with Dismal Outcome
The EPOR rearrangement, an uncommon cytogenetic abnormality linked to BCR::ABL1 -like B-ALL, is often underdiagnosed due to the absence of a robust...
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Small molecule inhibitors of the VEGF and tyrosine kinase for the treatment of cervical cancer
Cervical cancer accounts for most deaths due to cancer in women, majorly in develo** nations. The culprit behind this disease is the human...
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Safety and feasibility of early drinking water after general anesthesia recovery in patients undergoing daytime surgery
BackgroundPatients who are recovering from general anesthesia commonly exhibit symptoms such as dry lips, throat irritation, and thirst, prompting a...
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Fueling CARs: metabolic strategies to enhance CAR T-cell therapy
CAR T cells are widely applied for relapsed hematological cancer patients. With six approved cell therapies, for Multiple Myeloma and other B-cell...
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Two-year survival after scheduled extubation in patients with pneumonia or ARDS: a prospective observational study
PurposeTo report two-year survival after scheduled extubation in patients with pneumonia or acute respiratory distress syndrome (ARDS).
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Integrated proteomic and metabolomic profiling of lymph after trauma-induced hypercoagulopathy and antithrombotic therapy
BackgroundRoutine coagulation tests are not widely accepted diagnostic criteria of trauma-induced hypercoagulopathy (TIH) due to insensitivity....
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Performance of risk scores in predicting mortality at 3, 6, and 12 months in patients diagnosed with community-acquired pneumonia
BackgroundRisk scores (RS) evaluate the likelihood of short-term mortality in patients diagnosed with community-acquired pneumonia (CAP). However,...
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Revised cardiac risk index in predicting cardiovascular complications in patients receiving chronic kidney replacement therapy undergoing elective general surgery
IntroductionThe Revised Cardiac Risk Index (RCRI) is a six-parameter model that is commonly used in assessing individual 30-day perioperative...
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Analysis of risk factors of postoperative complication for non-small cell lung cancer
BackgroundThe relationship between risk factors of common postoperative complications after pulmonary resection, such as air leakage, atelectasis,...
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Highlights of ophthalmological manifestations in newly diagnosed acute leukemia: a correlation with hematological parameters
Acute leukemia is a hematological malignancy affecting different organ systems including the eye and orbit through direct infiltration of tissues or...
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Long-term consequences of positive surgical margin after partial nephrectomy for renal cell carcinoma: multi‐institutional analysis
IntroductionThe aim of the study was to determine the impact of positive surgical margins (PSM) after PN on very long-term recurrence in a...
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Recurrent catamenial hemoptysis: diagnostic challenges and management strategies—a case report
Catamenial hemoptysis (CH) is a rare, known disease for which diagnosis is crucial and treatment is indefinite. In this case report, CH was...
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Safety and efficacy of tract embolization using gelatin sponge particles in reducing pneumothorax after CT-guided percutaneous lung biopsy in patients with emphysema
BackgroundThe incidence of pneumothorax is higher in patients with emphysema who undergo percutaneous lung biopsy. Needle embolization has been shown...
