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  4. The RNA helicases DDX19A/B modulate selinexor sensitivity by regulating MCL1 mRNA nuclear export in leukemia cells

    Selinexor, a first-in-class exportin1 (XPO1) inhibitor, is an attractive anti-tumor agent because of its unique mechanisms of action; however, its...

    Tatsuya Terasaki, Yuichiro Semba, ... Takahiro Maeda in Leukemia
    Article 11 July 2024

  5. Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial

    Background

    Early fluid management in patients with advanced chronic kidney disease (CKD) and sepsis-induced hypotension is challenging with limited...

    Anselm Jorda, Ivor S. Douglas, ... Georg Gelbenegger in Critical Care
    Article Open access 11 July 2024

  6. Anti-TIM3 chimeric antigen receptor-natural killer cells preferentially target primitive acute myeloid leukemia cells with minimal fratricide and exhaustion

    Acute myeloid leukemia (AML) is an aggressive and genetically heterogeneous disease with poor clinical outcomes. Refractory AML is common, and...

    Phatchanat Klaihmon, Parinya Samart, ... Sudjit Luanpitpong in Experimental Hematology & Oncology
    Article Open access 11 July 2024

  7. Incompatibility of the short-acting benzodiazepine remimazolam with common perioperative medication

    Background

    Remimazolam is a relatively new benzodiazepine with growing use in procedural sedation and general anaesthesia. Initiated by case reports,...

    Pascal Hofmann, Lena Bachmann, ... Berthold Drexler in BMC Anesthesiology
    Article Open access 11 July 2024

  9. Relationship between epidural catheter migration beneath the skin and subcutaneous fat thickness assessed using postoperative CT imaging: a retrospective cross-sectional study

    Purpose

    The causes of epidural catheter migration beneath the skin have not been previously investigated. We hypothesized that greater subcutaneous...

    Natsumi Sakamoto, Mitsuhiro Matsuo, Tomonori Takazawa in Journal of Anesthesia
    Article 11 July 2024

  10. Bone Turnover Markers Levels in a Cohort of Egyptian Children with Sickle Cell Disease

    Bony complications are variable and common in sickle cell disease. Bone turnover markers are a reflection of bone new bone formation or degradation....

    Mona El-Tagui, Sameh Tawfik, ... Mariam Saad Nassim in Indian Journal of Hematology and Blood Transfusion
    Article 10 July 2024

  11. Clinical characteristics of extracorporeal cardiopulmonary resuscitation in China: a multicenter retrospective study

    Purpose

    Extracorporeal cardiopulmonary resuscitation (ECPR) might markedly increase the survival of selected patients with refractory cardiac arrest....

    Zhiyong Yuan, Ying Liu, ... **yan **ng in BMC Anesthesiology
    Article Open access 10 July 2024

  14. Health-related quality of life and symptoms of chronic myeloid leukemia patients after discontinuation of tyrosine kinase inhibitors: results from the EURO-SKI Trial

    Limited data is available on the health-related quality of life (HRQoL) and symptoms of patients with chronic myeloid leukemia (CML) who are in...

    Fabio Efficace, Francois-Xavier Mahon, ... Susanne Saussele in Leukemia
    Article 10 July 2024

  16. A retrospective analysis of treatment patterns, overall survival, and real-world disease-free survival in early-stage non-small cell lung cancer following complete resection

    Background

    Real-world data regarding patient characteristics, adjuvant treatment patterns, and long-term survival outcomes are needed to better...

    **aohan Hu, Diana Chirovsky, ... Ayman Samkari in BMC Pulmonary Medicine
    Article Open access 10 July 2024

  19. Effect of direct oral anticoagulant therapy on pulmonary artery clot dissolution in intermediate high-risk pulmonary thromboembolism

    Background

    Direct oral anticoagulants are the established drugs for treating pulmonary thromboembolism. The advantage of direct oral anticoagulants...

    Hiroya Hayashi, Akihiro Tsuji, ... Takeshi Ogo in Thrombosis Journal
    Article Open access 10 July 2024
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