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Medication nonadherence and associated factors in patients with tuberculosis in Wau, South Sudan: a cross- sectional study using the world health organization multidimensional adherence model
BackgroundTuberculosis medication nonadherence is a multi-dimensional public health problem with serious consequences worldwide. There is little...
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Physical Activity Interventions Framed by the Health Action Process Approach for Adults with Long-Term Conditions: A Sco** Review
BackgroundInterventions that use the Health Action Process Approach (HAPA) model show promise for increasing PA frequency, duration, and intensity....
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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
The causes of depression are complex, and the current diagnosis methods rely solely on psychiatric evaluations with no incorporation of laboratory...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....
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YAP/TAZ interacts with RBM39 to confer resistance against indisulam
The Hippo pathway and its downstream effectors, Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), are essential...
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Gras** the big picture: impact analysis of screening tools for timely referral for device-aided therapies
Several screening tools are available to assist general neurologists in the timely identification of patients with advanced Parkinson’s disease (PD)...
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Stroke heart injury: the effect of cerebral reperfusion treatment. A 3-year retrospective study
BackgroundCardiac involvement following an acute stroke (Stroke Heart Syndrome—SHS) is an established complication and it is linked to the...
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HIV1 drug resistance among patients experiencing first-line treatment failure in Ethiopia: protocol for a systematic review and meta-analysis
BackgroundThe emergence of HIV drug resistance presents a substantial challenge. Current antiretroviral treatments, along with current classes, face...
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Synthetic datasets for open software development in rare disease research
BackgroundGlobally, researchers are working on projects aiming to enhance the availability of data for rare disease research. While data sharing...
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Mediating role of gestational weight gain in the relationship between socioeconomic status and preterm birth: a Chinese population-based study
BackgroundThe modifiable mechanisms underlying the association between socioeconomic status (SES) and preterm birth remain unclear. This study aimed...
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The bidirectional association between the disability in activities of daily living and depression: a longitudinal study in Chinese middle-aged and older adults
AimDepression and disability in activities of daily living (ADL) are common in middle-aged and older adults. This study investigated the...
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The association between different impact exercises and osteoporosis: an analysis of data from the Taiwan biobank
Osteoporosis is a prevalent condition marked by reduced bone density and an elevated risk of fractures, especially among postmenopausal women....
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Reviewing hereditary connective tissue disorders: Proposals of harmonic medicolegal assessments
Hereditary connective tissue disorders (HCTDs) are a heterogeneous group of inherited diseases. These disorders show genetic mutations with loss of...
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Utilizing social media for community risk communication in megacities: analysing the impact of WeChat group information interaction and perception on communication satisfaction during the COVID-19 pandemic in Shanghai
BackgroundAgainst the backdrop of the global public health crisis, the COVID-19 pandemic has exposed significant disparities in the supply and demand...
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Jointly estimating epidemiological dynamics of Covid-19 from case and wastewater data in Aotearoa New Zealand
BackgroundTimely and informed public health responses to infectious diseases such as COVID-19 necessitate reliable information about infection...
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Intracranial vasculopathy: an important organ damage in young adult patients with late-onset Pompe disease
BackgroundLate-onset Pompe disease (LOPD) is mainly characterized by progressive limb-girdle muscle weakness and respiratory impairment, whereas...
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Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?
Purpose of ReviewThis review aims to critically examine how VLCKD affects plasma lipoprotein, lipid and cholesterol metabolism. Cardiovascular...