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Radiomics incorporating deep features for predicting Parkinson’s disease in 123I-Ioflupane SPECT
Purpose123 I-Ioflupane SPECT is an effective tool for the diagnosis and progression assessment of Parkinson’s disease (PD). Radiomics and deep...
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Deep learning based bilateral filtering for edge-preserving denoising of respiratory-gated PET
BackgroundResidual image noise is substantial in positron emission tomography (PET) and one of the factors limiting lesion detection, quantification,...
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Timing limits of ultrafast cross-luminescence emission in CsZnCl-based crystals for TOF-CT and TOF-PET
BackgroundGood timing resolution in medical imaging applications such as TOF-CT or TOF-PET can boost image quality or patient comfort significantly...
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Seracam: characterisation of a new small field of view hybrid gamma camera for nuclear medicine
BackgroundPortable gamma cameras are being developed for nuclear medicine procedures such as thyroid scintigraphy. This article introduces Seracam® –...
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Preliminary protocol for measuring the reproducibility and accuracy of flow values on digital PET/CT systems in [15O]H2O myocardial perfusion imaging using a flow phantom
BackgroundSeveral factors may decrease the accuracy of quantitative PET myocardial perfusion imaging (MPI). It is therefore essential to ensure that...
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A practical method for measuring planar spatial resolution with scatter on a CZT gamma camera
PurposeThis study proposes a practical method for evaluating 2D spatial resolution with scatter on a CZT planar detector gamma camera, which is...
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Kinetic model-informed deep learning for multiplexed PET image separation
BackgroundMultiplexed positron emission tomography (mPET) imaging can measure physiological and pathological information from different tracers...
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Improvements of 177Lu SPECT images from sparsely acquired projections by reconstruction with deep-learning-generated synthetic projections
BackgroundFor dosimetry, the demand for whole-body SPECT/CT imaging, which require long acquisition durations with dual-head Anger cameras, is...
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Position dependence of recovery coefficients in 177Lu-SPECT/CT reconstructions – phantom simulations and measurements
BackgroundAlthough the importance of quantitative SPECT has increased tremendously due to newly developed therapeutic radiopharmaceuticals, there are...
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DosePatch: physics-inspired crop** layout for patch-based Monte Carlo simulations to provide fast and accurate internal dosimetry
BackgroundDosimetry-based personalized therapy was shown to have clinical benefits e.g. in liver selective internal radiation therapy (SIRT). Yet,...
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Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
PurposeThis study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical...
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Improving diagnostic precision in amyloid brain PET imaging through data-driven motion correction
BackgroundHead motion during brain positron emission tomography (PET)/computed tomography (CT) imaging degrades image quality, resulting in reduced...
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An international phantom study of inter-site variability in Technetium-99m image quantification: analyses from the TARGET radioembolization study
BackgroundPersonalised multi-compartment dosimetry based on [ 99m Tc]Tc-MAA is a valuable tool for planning 90 Y radioembolization treatments. The...
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Signal separation of simultaneous dual-tracer PET imaging based on global spatial information and channel attention
BackgroundSimultaneous dual-tracer positron emission tomography (PET) imaging efficiently provides more complete information for disease diagnosis....
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Ultra-low foetal radiation exposure in 18F-FDG PET/CT imaging with a long axial field-of-view PET/CT system
PurposeLong axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With...
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Quantitative SPECT/CT imaging of actinium-225 for targeted alpha therapy of glioblastomas
BackgroundA new, alternative option for patients with recurrent glioblastoma is targeted alpha therapy (TAT), in the form of a local administration...
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The significance of partial volume effect on the estimation of hypoxic tumour volume with [18F]FMISO PET/CT
BackgroundThe purpose of this study was to evaluate how a retrospective correction of the partial volume effect (PVE) in [ 18 F]fluoromisonidazole...
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Evaluation of lesion contrast in the walk-through long axial FOV PET scanner simulated with XCAT anthropomorphic phantoms
BackgroundThis study evaluates the lesion contrast in a cost-effective long axial field of view (FOV) PET scanner, called the walk-through PET...
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Data-driven gating (DDG)-based motion match for improved CTAC registration
BackgroundRespiratory motion artefacts are a pitfall in thoracic PET/CT imaging. A source of these motion artefacts within PET images is the CT used...
