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The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff
BackgroundSharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways.
MethodsWe carried out...
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Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature
BackgroundCentral nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous...
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PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report
Peripheral intravenous central catheter (PICC) is a common tool for intravenous infusion for children who need central venous access. Although it is...
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Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer
BackgroundTo evaluate the clinical value of serum CEA levels and their implications on the diagnostic value of the conventional TNM staging system in...
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Zinc finger 259 gene polymorphisms in Egyptian patients with metabolic syndrome and its association with dyslipidemia
BackgroundZinc finger protein 1 (ZPR1), encoded by the ZNF259 gene, plays crucial roles in transcriptional regulation and cell cycle progression....
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Non-surgical vs. surgical treatment of distal radius fractures: a meta-analysis of randomized controlled trials
PurposeTo compare the clinical outcomes between nonsurgical and surgical treatment of distal radius fracture.
MethodsWe performed a systematic...
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Clinical characteristics of extracorporeal cardiopulmonary resuscitation in China: a multicenter retrospective study
PurposeExtracorporeal cardiopulmonary resuscitation (ECPR) might markedly increase the survival of selected patients with refractory cardiac arrest....
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Effect of NLRP3 gene knockdown on pyroptosis and ferroptosis in diabetic cardiomyopathy injury
Diabetic cardiomyopathy (DCM) is a chronic disease caused by diabetes mellitus, which is recognized as a worldwide challenging disease. This study...
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Dietary diversity and iron deficiency anemia among a cohort of singleton pregnancies: a cross-sectional study
BackgroundIron deficiency anemia (IDA) is considered one of the most common medical disorders observed during pregnancy. In low- and middle-income...
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Randomized investigation of increased dialyzer membrane hydrophilicity on hemocompatibility and performance
BackgroundHemodialyzers should efficiently eliminate small and middle molecular uremic toxins and possess exceptional hemocompatibility to improve...
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Comparison of low versus high (standard) intraabdominal pressure during laparoscopic colorectal surgery: systematic review and meta-analysis
BackgroundTo evaluate outcomes of low with high intraabdominal pressure during laparoscopic colorectal resection surgery.
MethodsA systematic search...
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Estimation of age and sex from fingernail clip**s by using ATR-FTIR spectroscopy coupled with chemometric interpretation
Fingernails can act as important forensic evidence as they can be a source of DNA that may link the victim or accused to the crime scene and may also...
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Refractory type 1 plastic bronchitis in a child; case report
BackgroundPlastic bronchitis (PB) is a rare pediatric pulmonary condition characterized by the production of branching bronchial casts that cause...
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Trichohepatoenteric syndrome type 1: expanding the clinical spectrum of THES type 1 due to a homozygous variant in the SKIC3 gene
Trichohepatoenteric syndrome (THES), also known as phenotypic diarrhea or syndromic diarrhea, is a rare autosomal recessive genetic disorder caused...
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Minimally invasive approach in a rare emergency surgery, gallbladder perforation
BackgroundGallbladder perforations are challenging to manage for surgeons due to their high morbidity and mortality, rarity, and surgical approach....
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Progress in the Application of Hydrogels in Intervertebral Disc Repair: A Comprehensive Review
Purpose of ReviewIntervertebral disc degeneration (IVDD) is a common orthopaedic disease and an important cause of lower back pain, which seriously...
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Extrakorporale Verfahren bei Vergiftungen
In rare cases, intoxicated patients may require an extracorporeal procedure for enhanced toxin elimination. The Extracorporeal Treatments in...
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Tremor as a Neuropsychiatric Manifestation of Systemic Lupus Erythematosus: A Case Report and Review of Related Literature
Movement disorders in neuropsychiatric systemic lupus erythematosus (NPSLE) are rare. Chorea remains the predominant phenomenology whereas tremors...
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Molecular circadian clock disruption in the leukocytes of individuals with type 2 diabetes and overweight, and its relationship with leukocyte–endothelial interactions
Aims/hypothesisAlterations in circadian rhythms increase the likelihood of develo** type 2 diabetes and CVD. Circadian rhythms are controlled by...