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Lenalidomide and pomalidomide modulate hematopoietic cell expansion and differentiation in the presence of MSC
Cytopenia is a well-documented complication in the treatment of hematological malignancies with lenalidomide and pomalidomide. Although prior studies...
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Nourishing Physical Productivity and Performance On a Warming Planet - Challenges and Nutritional Strategies to Mitigate Exertional Heat Stress
Purpose of ReviewClimate change is predicted to increase the frequency and severity of exposure to hot environments. This can impair health, physical...
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ETV6::ABL1 positive myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (MLN-TK) with blast crisis treated with flumatinib mesylate
ETV6::ABL1 fusion gene is a rare but recurrent genomic rearrangement in hematological malignancies with poor prognosis. Here, we report 1 case of Ph...
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Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)
BackgroundBilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...
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The diagnostic and prognostic value of tartrate-resistant acid phosphatase isoform 5b for giant cell tumor of bone
BackgroundSerum level of tartrate-resistant acid phosphatase 5b (TRACP5b) is an excellent serum marker of bone resorption. In patients with giant...
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Comparative analysis of reduced toxicity conditioning regimens between fludarabine plus melphalan and fludarabine plus busulfex in adult patients with acute lymphoblastic leukemia
Reduced-toxicity conditioning (RTC) regimens aim to mitigate regimen-related toxicity while maintaining anti-leukemic efficacy in allogeneic...
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Super T2-FLAIR mismatch sign: a prognostic imaging biomarker for non-enhancing astrocytoma, IDH-mutant
PurposeThe T2-FLAIR mismatch sign is a highly specific diagnostic imaging biomarker for astrocytoma, IDH-mutant. However, a definitive prognostic...
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Imaging of sports injuries in adolescents
Musculoskeletal injuries in adolescents tend to occur in particular locations and have distinct characteristics, as they affect an immature skeleton....
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Ethical Considerations and Equipoise in Cancer Surgery
The changing landscape of cancer surgery requires ongoing consideration of ethical issues to ensure patient-centered care and fair access to...
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MICAL1 promotes the proliferation in acute myeloid leukemia and is associated with clinical prognosis and immune infiltration
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has a poor prognosis and a high rate of relapse. Dysregulated...
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Enhanced γ-H2AX Foci Frequency and Altered Gene Expression in Participants Exposed to Ionizing Radiation During I-131 Nuclear Medicine Procedures
PurposeIonizing radiation-based technologies are extensively used in the diagnosis and treatment of diseases. While utilizing the technologies,...
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Rare case of myelodysplastic syndrome with excess blasts 2 develo** after adjuvant chemoradiotherapy for triple-negative breast cancer in a patient with Bloom syndrome
IntroductionBloom syndrome (BS) is a rare autosomal recessive disorder caused by a loss-of-function mutation in the BLM gene encoding an RecQ...
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A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion
BackgroundMost patients treated with the standard dosing protocol (SDP) of hepatic arterial infusion (HAI) floxuridine require dose holds and...
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Indocyanine Green Fluorescence-Guided Laparoscopic Anatomical Segmentectomy of Liver Segment 6: Surgical Strategy and Technical Details
BackgroundBecause of the complex anatomy of the right posterior hepatic pedicle, there have been few reports on standardized laparoscopic portal...