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Phenotypic and mutational spectrum of 17 Chinese patients with Menkes Disease
BackgroundMenkes Disease (MD) is a fatal X-linked recessive disorder caused by mutations in the ATP7A gene. Severe cases typically die before the age...
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Elevated plasma neurofilament light was associated with multi-modal neuroimaging features in Alzheimer’s disease signature regions and predicted future tau deposition
BackgroundNeurofilament Light (NfL) is a biomarker for early neurodegeneration in Alzheimer’s disease (AD). This study aims to examine the...
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Second-look surgery in postoperative pediatric low-grade glioma
ObjectiveTo review the literature on second-look surgery in pediatric low-grade gliomas (LGG) with a view to presenting both sides of the picture of...
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Successful treatment with efgartigimod as an add-on therapy in acute attack of anti-AQP4 antibody-positive NMOSD: a case report
BackgroundNeuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune demyelinating disease characterized by recurrent myelitis and optic...
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Single-centre real-life observational study on mortality and outcomes: decompressive craniectomy and brain death in traumatic brain injury, haemorrhage, and other cerebral diseases
BackgroundDecompressive hemicraniectomy (DHC) is used after severe brain damages with elevated, refractory intracranial pressure (ICP). In a non...
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Plasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma
PurposeGlioma-associated epilepsy affects a significant proportion of glioma patients, contributing to disease progression and diminished survival...
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Radiosurgical thalamotomy for the management of tremors: a systematic review and meta-analysis
Medical treatment for tremors may include beta-blockers, primidone, dopaminergic, and anticholinergic drugs but it frequently leads to...
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Beyond nimodipine: advanced neuroprotection strategies for aneurysmal subarachnoid hemorrhage vasospasm and delayed cerebral ischemia
The clinical management of aneurysmal subarachnoid hemorrhage (SAH)-associated vasospasm remains a challenge in neurosurgical practice, with its...
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Rate of abnormalities in quantitative MR neuroimaging of persons with chronic traumatic brain injury
BackgroundMild traumatic brain injury (mTBI) can result in lasting brain damage that is often too subtle to detect by qualitative visual inspection...
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Evaluation of 3D T1-weighted spoiled gradient echo MR image quality using artificial intelligence image reconstruction techniques in the pediatric brain
PurposeTo assess image quality and diagnostic confidence of 3D T1-weighted spoiled gradient echo (SPGR) MRI using artificial intelligence (AI)...
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AChR-seropositive myasthenia gravis in muscular dystrophy: diagnostic pitfalls and clinical management challenges
The co-occurrence of genetic myopathies with myasthenia gravis (MG) is extremely rare, however a few studies have been reported. We aim to explore...
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The effect of transcranial magnetic stimulation on cognitive function in post-stroke patients: a systematic review and meta-analysis
Background and ObjectiveTranscranial magnetic stimulation (TMS) is considered as a promising treatment option for post-stroke cognitive impairment...
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Are the facet joint parameters risk factors for cage subsidence after TLIF in patients with lumbar degenerative spondylolisthesis?
PurposeTo assess whether preoperative facet joint parameters in patients with degenerative lumbar spondylolisthesis (DS) are risk factors for cage...
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Atypical and anaplastic meningiomas in the later decades of life: A national cancer database analysis
PurposeWe conducted a National Cancer Database (NCDB) study to investigate the epidemiological characteristics and identify predictors of outcomes...
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Trans-temporal trans-choroidal resection of thalamic and thalamopeduncular tumors: how I do it
BackgroundSurgical resection is the cornerstone of treatment for low-grade tumors, albeit total excision is beneficial. As the thalamus is...
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Calvarial bone graft for craniovertebral junction fixation in children
PurposeTo evaluate the efficacy of calvarial graft (CG) in craniovertebral fusion procedures in children at a single single center.
Methods ...
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Effect of intravenous thrombolysis before endovascular therapy on outcomes in acute ischemic stroke with large core: a systematic review and meta-analysis
ObjectiveTo investigate the effect of intravenous thrombolysis (IVT) before endovascular therapy (EVT) on outcomes in acute ischemic stroke of large...
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Local adjuncts to minimally invasive endoscopic interventions for benign laryngotracheal stenosis: a meta-analysis
BackgroundBenign laryngotracheal stenosis is widely managed with minimally invasive endoscopic interventions, such as laser incision or excision...
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Surgical outcomes of trigonal intraventricular meningiomas: a single-centre study
Trigonal meningiomas are rare intraventricular tumours that present a surgical challenge. There is no consensus on the optimal surgical approach to...
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Efficacy of pain management strategies in adults with Amyotrophic Lateral Sclerosis (ALS): A Systematic Review
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscle weakness. Presence of pain in ALS patients is...
