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  1. The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice

    Background

    This study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...

    Dong Xu, Lin Sui, ... Li** Wang in BMC Medicine
    Article Open access 12 July 2024
  2. Synergistic induction of mitotic pyroptosis and tumor remission by inhibiting proteasome and WEE family kinases

    Mitotic catastrophe (MC), which occurs under dysregulated mitosis, represents a fascinating tactic to specifically eradicate tumor cells. Whether...

    Zhan-Li Chen, Chen **e, ... Shi-Mei Zhuang in Signal Transduction and Targeted Therapy
    Article Open access 12 July 2024
  3. Hemophagocytic Lymphohistiocytosis for the Inpatient Dermatologist

    Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening condition characterized by dysregulation of the immune system leading to...

    Bliss Colao, Grace Hingtgen, ... Kiran Motaparthi in Current Dermatology Reports
    Article 12 July 2024
  4. Diagnostic performance of coronary calcifications on CT to rule out acute coronary syndrome in the emergency department

    Background

    At present, the diagnosis of acute coronary syndrome (ACS) can be made by emergency physicians using the usual complementary tests, since...

    Julie Paget Sentagne, Mickaël Ohana, ... Sabrina Kepka in BMC Emergency Medicine
    Article Open access 12 July 2024
  5. Fragile X Syndrome and FMR1 premutation: results from a survey on associated conditions and treatment priorities in Italy

    Background and objectives

    Fragile X Syndrome (FXS) is the most common cause of inherited intellectual disability, caused by CGG-repeat expansions...

    Federica Alice Maria Montanaro, Paolo Alfieri, ... Stefano Vicari in Orphanet Journal of Rare Diseases
    Article Open access 12 July 2024
  6. Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus

    Aims

    Dipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...

    Lijia Zhao, Jie Meng, ... **n Liu in European Journal of Medical Research
    Article Open access 12 July 2024
  7. Real world treatment outcomes in polypoidal choroidal vasculopathy in a Caucasian population of British ethnicity

    Purpose

    To assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal...

    Gabriella De Salvo, Suresh Thulasidharan, ... Rino Frisina in Eye
    Article 12 July 2024
  8. Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway

    Background

    Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The...

    Hai-Hua Liu, Wei Wei, ... Peng-Fei Zhang in BMC Cardiovascular Disorders
    Article Open access 12 July 2024
  9. Basal FSH values are positively associated with aneuploidy incidence in pre-advanced maternal age (AMA) but not in AMA patients

    Purpose

    To assess the impact of maternal age on the association between maternal basal FSH and aneuploidy.

    Methods

    A retrospective study including...

    Catherine K. Jacobs, Mariana Nicolielo, ... Jose Buratini in Journal of Assisted Reproduction and Genetics
    Article 12 July 2024
  10. Exploring paramedics’ lived experiences in confrontation with patients’ death during missions: a phenomenological study

    Background

    Emergency personnel are the first line of emergency response systems to respond to emergencies; in essence, they are usually exposed to a...

    Milad Ahmadi Marzaleh, Mahmoudreza Peyravi, ... Hossein Avazaghaei in BMC Emergency Medicine
    Article Open access 12 July 2024
  11. Improving the introduction of telemedicine in pre-hospital emergency medicine: understanding users and how acceptability, usability and effectiveness influence this process

    Introduction

    Increasing numbers of ambulance calls, vacant positions and growing workloads in Emergency Medicine (EM) are increasing the pressure to...

    Seán O’Sullivan, Jennifer Krautwald, Henning Schneider in BMC Emergency Medicine
    Article Open access 12 July 2024
  12. Mucinous tubular and spindle renal cell carcinoma revealed by a trauma of the kidney: a case report

    Background

    Mucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health...

    Kays Chaker, Mahdi Marrak, ... Yassine Nouira in Journal of Medical Case Reports
    Article Open access 12 July 2024
  13. Non-emergency department (ED) interventions to reduce ED utilization: a sco** review

    Background

    Emergency department (ED) crowding is a global burden. Interventions to reduce ED utilization have been widely discussed in the literature,...

    Målfrid A. Nummedal, Sarah King, ... Lars Petter Bjørnsen in BMC Emergency Medicine
    Article Open access 12 July 2024
  14. A randomized controlled trial to assess if changing sleep timing can improve glucose metabolism in people with prediabetes and type 2 diabetes

    Background

    Social jetlag is a chronic disruption of sleep timing that is characterized by different sleep timing during workdays and free days. Social...

    Emma J. Bouman, Romy Slebe, ... Femke Rutters in Trials
    Article Open access 12 July 2024
  15. Woven coronary artery with acquired etiology: the natural history documented by serial angiography and optical coherence tomography

    Woven coronary artery (WCA) is a rare anomaly and its etiology remains speculative. Both congenital and acquired factors are considered to be...

    Jiannan Li, **aoli Wang, ... Hanjun Zhao in BMC Cardiovascular Disorders
    Article Open access 12 July 2024
  16. Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)

    Background

    Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...

    Shan-Shan Huang, Yi Ding, ... Zhou-**n Yang in European Journal of Medical Research
    Article Open access 12 July 2024
  17. A cognitive-behavioral treatment for suicide prevention among adults with schizophrenia spectrum disorders in community mental health: Study protocol for a pilot feasibility and acceptability randomized clinical trial

    Background

    Suicide is among the leading causes of death for adults with schizophrenia spectrum disorders (SSDs), and there is a paucity of...

    Lindsay A. Bornheimer, Juliann Li Verdugo, ... Joseph A. Himle in Pilot and Feasibility Studies
    Article Open access 12 July 2024
  18. BCORL1, POF1B, and USP9X copy number variation in women with idiopathic diminished ovarian reserve

    Purpose

    To analyze the copy number variation (CNV) in the X-linked genes BCORL1 , POF1B , and USP9X in idiopathic diminished ovarian reserve (DOR).

    ...
    Cristiana Libardi Miranda Furtado, Murilo Racy Soares, ... Rosana Maria dos Reis in Journal of Assisted Reproduction and Genetics
    Article 12 July 2024
  19. Healthcare delivery to patients from culturally and linguistically diverse backgrounds in emergency care: a sco** review protocol

    Background

    Worldwide, the culturally and linguistically diverse (CALD) population is increasing, and is predicted to reach 405 million by 2050. The...

    Ya-Ling Huang, Sarah Thorning, ... Julia Crilly in Systematic Reviews
    Article Open access 12 July 2024
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