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Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-risk
The mitochondrial cascade hypothesis of Alzheimer’s disease (AD) has been portrayed through molecular, cellular, and animal studies; however large...
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The abortion trend after the pronatalist turn of population policies in Iran: a systematic review from 2005 to 2022
ObjectiveGiven Iran’s recent shift towards pronatalist population policies, concerns have arisen regarding the potential increase in abortion rates....
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A multidisciplinary group-based survivorship intervention for those living with multiple myeloma: a feasibility study
BackgroundWhile multiple myeloma continues to be an incurable cancer, advances in its understanding and management have led to significantly improved...
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Using the illness-death model to estimate age- and sex-standardized incidence rates of diabetes in Mexico from 2003 to 2015
BackgroundWe aimed to estimate the age-specific and age-standardized incidence rate of diabetes for men and women in Mexico between 2003 and 2015,...
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The effectiveness of the WHO school mental health package in promoting mental health literacy among secondary school teachers in Qatar: a randomized controlled trial
Teachers’ mental health literacy (MHL) is fundamental for recognizing and assisting students with mental disorders. The aim of this study was to...
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Risk factors associated with underweight in children aged one to two years: a longitudinal study
BackgroundUnderweight is a prevalent health issue in children. This study aimed to identify factors associated with underweight in children aged 1–2...
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SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
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Factors affecting decisions of an HMO Drug Exemptions Committee on individual patient requests for coverage of non-formulary drugs
BackgroundIn Israel, coverage of health needs is delivered by four health maintenance organizations (HMOs), which are budgeted by the government...
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Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study
BackgroundThe heart can be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to summarize the clinical features and...
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The hospital emigration to another region in the light of the environmental, social and governance model in Italy during the period 2004-2021
The following article presents an analysis of the impact of the Environmental, Social and Governance-ESG determinants on Hospital Emigration to...
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Willingness to receive mpox vaccine among men who have sex with men: a systematic review and meta-analysis
BackgroundSince May 2022, mpox outbreaks have been occurring in non-mpox endemic areas, with the main population affected being men who have sex with...
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Moving from idea to reality: The barriers and enablers to implementing Child and Family Hubs policy into practice in NSW, Australia
BackgroundAdverse childhood experiences can impact physical and mental health throughout the lifespan. To support families experiencing adversity and...
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Impact of acid and laser etching of enamel on microleakage in different adhesive systems
This study aimed to evaluate the microleakage of light-cured and self-cured adhesives on enamel surfaces selectively etched with Er, Cr: YSGG laser...
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Efficacy of iron supplementation on physical capacity in non-anaemic iron-deficient individuals: protocol for an individual patient data meta-analysis
BackgroundA deficiency in iron stores is associated with various adverse health complications, which, if left untreated, can progress to states of...
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Prompt closure versus gradual weaning of external ventricular drain for hydrocephalus following aneurysmal subarachnoid haemorrhage: a statistical analysis plan for the DRAIN randomised clinical trial
BackgroundInsertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid...
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Theory of change for addressing sex and gender bias, invisibility and exclusion in Australian health and medical research, policy and practice
Sex and gender are inadequately considered in health and medical research, policy and practice, leading to preventable disparities in health and...
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A protocol for the formative evaluation of the implementation of patient-reported outcome measures in child and adolescent mental health services as part of a learning health system
BackgroundMental health conditions affect one in seven young people and research suggests that current mental health services are not meeting the...
