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A novel fluffy PLGA/HA composite scaffold for bone defect repair
Treatment of bone defects remains crucial challenge for successful bone healing, which arouses great interests in designing and fabricating ideal...
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Hydroxyapatite−loaded starch/polyvinyl alcohol scaffold for bone regeneration application: preparation and characterization
Hydroxyapatite (HA) embedded in polymer-based bone scaffold exhibits excellent medical properties for bone healing. Indeed, limited studies have...
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Biodegradable Nanocomposite as Advanced Bone Tissue Scaffold
The continuous advancements in nanotechnology, understanding of reinforcement procedures of nanoscale materials, and related fabrication technologies...
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Evaluating the effect of cryopreservation, cell migration and perfused media on degradation of porous scaffold
The degradation of scaffolds is a critical aspect in tissue engineering and regenerative medicine. Various factors that influence the degradation of...
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Biophysical-driven piezoelectric and aligned nanofibrous scaffold promotes bone regeneration by re-establishing physiological electrical microenvironment
The initial healing stages of bone fracture is a complex physiological process involving a series of spatially and temporally overlap** events,...
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Incorporation of chondroitin sulfate into macroporous bacterial cellulose scaffold for improved bioactivity
Lack of bioactivity limits the applications of bacterial cellulose (BC) in biomedical fields. In this study, we report the facile preparation of a...
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Delivery of letrozole-encapsulated niosomes via a 3D bioprinting gelatin–alginate scaffold for potential breast cancer treatment
3D printing technology is a powerful tool in scaffold engineering for biomedical applications, especially in anticancer activities and drug delivery....
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Additively manufactured 3D short carbon fiber scaffold for thermoset composites
Short-fiber-reinforced polymer composites offer advantages, like flexibility in complex geometries and cost-effectiveness, but typically exhibit...
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Electrospun dimethyloxallylglycine sustained release scaffold for promoting the migration and multidirectional differentiation of stem cells from the apical papilla
Dental pulpitis, a common dental disease, poses a significant challenge for modern dentistry because of the intricate framework and limited...
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A tri-layer decellularized, dehydrated human amniotic membrane scaffold supports the cellular functions of human tenocytes in vitro
Differences in scaffold design have the potential to influence cell-scaffold interactions. This study sought to determine whether a tri-layer design...
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A bi-layer electrospun polyurethane/silicone membrane scaffold: drug delivery and cytotoxicity studies
In this study, a bi-layer scaffold combining polyurethane nanofibrous and silicone membrane layers was produced. Chemical, morphological and physical...
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Biosoluble ceramic fiber reinforced poly(L-lactic acid) bone scaffold: degradation and bioactivity
Poly (l-lactic acid) (PLLA) exhibits great potential as a kind of scaffold material for bone defect repair because of its good biocompatibility and...
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3D Sacrificial Microchannels by Scaffold Removal Process for Electrical Characterization of Electrolytes
3D printing technology is promising for the fabrications of microfluidic devices. For both research and educational purposes, the efficient...
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Fabrication and characterization of nano-particle biomaterial scaffold for treating burn wounds
Healing burn wounds is a complex process and challenging to design an ideal scaffold for tissue regeneration. The inflammatory phase is critical in...
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Chondrogenic potential of manganese-loaded composite scaffold combined with chondrocytes for articular cartilage defect
Cartilage is an alymphatic, avascular and non-innervated tissue. Lack of potential regenerative capacity to reconstruct chondral defect has...
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Oligonucleotide nanoassemblies with allyl bromide scaffold-based small molecules
The development of oligonucleotide nanoassemblies with small molecules has shown great potential in bio-medical applications. However, the...
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In Vivo Evaluation of the Regenerative Capacity of a Nanofibrous, Prevascularized, Load-Bearing Scaffold for Bone Tissue Engineering
PurposeDue to the increasing number of orthopedic injuries occurring each year, there is a critical need for better treatment of improperly healed...
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Nanofiber Scaffold-Based Tissue Engineering for the Treatment of Acute Liver Failure
Acute liver failure (ALF) has a mortality rate of more than 40%. Currently, orthotopic liver transplantation is the sole clinical treatment for ALF,...
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3D Printing-Electrospinning Hybrid Nanofibrous Scaffold as LEGO-Like Bricks for Modular Assembling Skeletal Muscle-on-a-Chip Functional Platform
Organ-on-a-chip stands as a pivotal platform for skeletal muscle research while constructing 3D skeletal muscle tissues that possess both macroscopic...
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3D printed OCP bone scaffold with alginate enhancing osteogenic differentiation in MG-63 cells
3D printing technology using calcium phosphate materials such as octacalcium phosphate (OCP, Ca 8 H 2 [PO 4 ] 6 ·5H 2 O) has emerged as a precise approach for...
