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Targeting and sensitizing MDR cancer by an MMP2 and pH dual-responsive ZnO-based nanomedicine
Zinc oxide nanoparticles (ZnO NPs) have been known as a therapeutic agent and drug delivery system for treating various diseases, including...
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Delivery of letrozole-encapsulated niosomes via a 3D bioprinting gelatin–alginate scaffold for potential breast cancer treatment
3D printing technology is a powerful tool in scaffold engineering for biomedical applications, especially in anticancer activities and drug delivery....
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Responsive biomaterials: optimizing control of cancer immunotherapy
Immunotherapy has emerged as an eminent and effective modality in the treatment of cancer. However, current cancer immunotherapies lack spatial and...
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Microenvironmental cue-regulated exosomes as therapeutic strategies for improving chronic wound healing
Exosomes, which are nanoscale vesicles secreted by almost all cell types via paracrine pathways, play a crucial role in intercellular communication....
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A site-oriented nanosystem for active transcellular chemo-immunotherapy to prevent tumor growth and metastasis
Immunotherapy has shown promising potential in cancer therapy; however, poor delivery by nanocarriers and insufficient immune response in tumors have...
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Tumor Microenvironment and Intracellular Signal-Activated Nanocomposites for Anticancer Drug Delivery
The use of nanomaterials for drug delivery and cancer therapy has well established itself over the past decades. Compared with free...
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Size-transformable nanoparticles with sequentially triggered drug release and enhanced penetration for anticancer therapy
There are several limitations to the application of nanoparticles in the treatment of cancer, including their low drug loading, poor colloidal...
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Doxorubicin-loaded liposomes surface engineered with the matrix metalloproteinase-2 cleavable polyethylene glycol conjugate for cancer therapy
BackgroundColorectal cancer is one of the prominent leading causes of fatality worldwide. Despite recent advancements within the field of cancer...
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Nutrient-delivery and metabolism reactivation therapy for melanoma
To fulfil the demands of rapid proliferation, tumour cells undergo significant metabolic alterations. Suppression of hyperactivated metabolism has...
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Eugenol-loaded mesoporous silica nanoparticles enhance the sensitivity of cisplatin against AGS human gastric adenocarcinoma cell line
Gastric cancer is one of the most common cancers with a high mortality rate worldwide. Eugenol possesses antioxidant, anti-inflammatory,...
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Delivery of melittin-loaded niosomes for breast cancer treatment: an in vitro and in vivo evaluation of anti-cancer effect
BackgroundMelittin, a peptide component of honey bee venom, is an appealing candidate for cancer therapy. In the current study, melittin,...
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Hydrogels for RNA delivery
RNA-based therapeutics have shown tremendous promise in disease intervention at the genetic level, and some have been approved for clinical use,...
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Extracellular vesicle–matrix interactions
The extracellular matrix (ECM) harbours various signals to control cellular functions and the materiality of tissues. Most efforts to synthetically...
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Research progress of nanomaterial-mediated photodynamic therapy in tumor treatment
Photodynamic therapy (PDT) is a new approach to destroy tumor over past decades due to its high selectivity and minimal invasiveness....
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Promise of gold nanomaterials as a lung cancer theranostic agent: a systematic review
Lung cancer is considered to be the second most prevalent form of cancer in the world and is associated with high mortality rates. Early diagnosis...
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Magneto-acoustic protein nanostructures for non-invasive imaging of tissue mechanics in vivo
Measuring cellular and tissue mechanics inside intact living organisms is essential for interrogating the roles of force in physiological and disease...
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Liposomes in Drug Delivery: Status and Advances
Liposomal drug delivery system has made evident breakthrough and innovation in the fields of drug treatment. The objectives of this chapter are to...
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Methacrylic Acid-Based Regenerative Biomaterials: Explorations into the MAAgic
Methacrylic acid (MAA)-based biomaterials are the archetype regenerative biomaterial. Without added cells or biomolecules, MAA-based materials...
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mRNA nanodelivery systems: targeting strategies and administration routes
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid (mRNA) vaccines, mRNA therapeutics have gained significant...
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Pore-engineered nanoarchitectonics for cancer therapy
Nanoarchitectonics describes the integration of nanotechnology with other fields as a postnanotechnology concept that elevates it to material...
