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Targeted drug-loaded PLGA-PCL microspheres for specific and localized treatment of triple negative breast cancer
The paper presents the results of the experimental and analytical study of targeted drug-loaded polymer-based microspheres made from blend polymer of...
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Glycol chitosan amphiphile nanotheranostic system for ultrasound-mediated localized release and biodistribution of doxorubicin
Ultrasound-mediated delivery has garnered attention as a noninvasive modality for localized drug delivery in cancer. Doxorubicin, a chemotherapeutic...
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Ultra-efficient MCF-7 cell ablation and chemotherapy-integrated electrothermal therapy with DOX–WS2–PEG–M13 nanostructures
Clinical trials have generated encouraging outcomes for the utility of thermal agents (TAs) in cancer thermal therapy (TT). Although the fast...
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Gold-capsuled polymeric nanomedicine for synergistic breast cancer photo-chemotherapy
Photo-chemotherapy is a potent anticancer therapeutic approach. Herein, we designed a gold-capsulated lapatinib nanomedicine for breast cancer...
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Microwave triggered multifunctional nanoplatform for targeted photothermal-chemotherapy in castration-resistant prostate cancer
Lacking a precise targeting strategy, castration-resistant prostate cancer (CRPC) is still hard to be treat effectively. Exploring treatment options...
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Anti-cancer liposomal chemophototherapy using bilayer-localized photosensitizer and cabazitaxel
Photodynamic therapy (PDT) is a non-invasive tumor ablation modality that can be enhanced in combination with concurrent chemotherapy. Previously, we...
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Mild hyperthermia synergized chemotherapy by Bi2Se3/MoSe2 nanosaucers for cancer treatment with negligible thermal resistance
Harsh photothermal temperatures (> 50 °C) caused heating damage to the normal tissues and induced thermal resistance in cancer cells, which...
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Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy
BackgroundClaudin-4 (CLDN4), a tight junction protein, is overexpressed in several types of cancer, and is considered a biomarker for cancer-targeted...
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Mesothelin targeted nano-system enhanced chemodynamic therapy and tirapazamine chemotherapy via lactate depletion
The enhanced permeability and retention (EPR) effect alone is not enough for nanoparticles to reach the target. Combination of active and passive...
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Electrospun nanofibrous mats loaded with gemcitabine and cisplatin suppress bladder tumor growth by improving the tumor immune microenvironment
AbstractThe perplexing issues related to positive surgical margins and the considerable negative consequences associated with systemic chemotherapy...
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Fabrication and application of cisplatin-loaded mesoporous magnetic nanobiocomposite: a novel approach to smart cervical cancer chemotherapy
There are significant challenges in develo** drug carriers for therapeutic perspective. We have investigated a novel nanocarrier system, based on...
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Safety evaluation of biopolymer immune implants in rats and rabbits as well as therapeutic effects on gastric cancer peritoneal metastasis carcinoma
Peritoneal metastasis carcinoma (PMC), as an extremely aggressive malignant tumor with high metastatic potential, typically exhibits an average...
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Potential anti-tumor activity of 13.56 MHz alternating magnetic hyperthermia and chemotherapy on the induction of apoptosis in human colon cancer cell lines HT29 and HCT116 by up-regulation of Bax, cleaved caspase 3&9, and cleaved PARP proteins
BackgroundThe purpose of the present study was to evaluate the efficacy of chemo-magnetic hyperthermia (MH), a combination of alternating magnetic...
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Photothermally modulated drug release kinetics for pH and thermo-responsive hydrogel system
Injectable hydrogel systems to achieve controlled drug release for localized chemotherapy are emerging modality for cancer therapy. Here, an...
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Trinity immune enhancing nanoparticles for boosting antitumor immune responses of immunogenic chemotherapy
Certain chemo drugs have been reported to potentially induce tumor-specific immune recognition by triggering immunogenic cell death (ICD), which...
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Mesoporous silica decorated with platinum nanoparticles for drug delivery and synergistic electrodynamic-chemotherapy
Electrodynamic therapy (EDT) is a conceptually new cancer treatment approach recently proposed by our group. During EDT, the electro-driven catalytic...
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Albumin-based multidrug delivery system enriched in Golgi apparatus against metastatic breast cancer
Breast cancer and metastasis remain great challenges in clinical therapy. Compared with monotherapy, combination therapy, especially mediated by...
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Applications of Nanoscience and Nanotechnology in Oral Cancer: A Review
Today, cancer is a significant health risk. It is the second most common cause of death worldwide and a serious issue for public health. Oral Cancer...
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Unlocking the potential of mesoporous silica nanoparticles in breast cancer treatment
AbstractBreast cancer is the most common cancer among women and is typically managed through surgery, radiation therapy, and chemotherapy. However,...
