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Comparison of Gentamicin and Dexamethasone Release Kinetics from Poly(Lactic Acid) (PLA) Microspheres for Drug Delivery Systems
A drug release that is controlled and can be kept constant within the therapeutic range over an optimal period of time at a predictable rate, as well...
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Dexamethasone release from hyaluronic acid microparticle and proanthocyanidin-gelatin hydrogel in sciatic tissue regeneration
Biodegradable microparticles are useful vehicles for the controlled release of bioactive molecules in drug delivery, tissue engineering and...
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Dexamethasone-loaded keratin films for ocular surface reconstruction
Amniotic membrane (AM) is often applied as a substitute material during ocular surface reconstruction. However, since AM has several disadvantages,...
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Effects of Dexamethasone-In Situ Forming Implant (ISFI) on the Differentiation Process of Human Dental Pulp Stem Cells to Osteoblasts
BackgroundDental pulp stem cells (DPSCs) of humans show a high ability to proliferate and differentiate. Therefore, due to their reproducibility and...
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Preparation and characterization of dexamethasone polymeric nanoparticle by membrane emulsification method
The objective of this study was to prepare and characterize dexamethasone polymeric nanoparticles by membrane emulsification method. Shirasu porous...
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Effect of dexamethasone as osteogenic supplementation in in vitro osteogenic differentiation of stem cells from human exfoliated deciduous teeth
In in vitro culture systems, dexamethasone (DEX) has been applied with ascorbic acid (ASC) and β-glycerophosphate (βGLY) as culture media...
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Flexible multifunctional titania nanotube array platform for biological interfacing
AbstractThe current work presents a novel flexible multifunctional platform for biological interface applications. The use of titania nanotube arrays...
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Application of Drug Liposomes in the Hormone Therapy
Glucocorticoids (GCs) have been proven to be very potent in treating chronic inflammatory diseases such as rheumatoid arthritis. The treatment of...
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ROS-responsive nanoparticles targeting inflamed colon for synergistic therapy of inflammatory bowel disease via barrier repair and anti-inflammation
The destruction of the intestinal barrier is likely to cause an increase in intestinal permeability and cause pathological damage. Numerous studies...
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Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury
Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming inflammation in the myocardium. Herein, cardiomyocyte-targeted...
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Inducing Macrophages M2 Polarization by Dexamethasone Laden Mesoporous Silica Nanoparticles from Titanium Implant Surface for Enhanced Osteogenesis
The study conveys an idea to enhance the osseointegration of titanium implant (Ti) through modulating macrophages M2 polarization. The ~ 100 nm...
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Drug infused Al2O3-bioactive glass coatings toward the cure of orthopedic infection
A unique implant coated substrate with dual-drug-eluting system exhibiting antibacterial, anti-inflammatory, and bone regenerative capacity has been...
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Sprayable nanodrug-loaded hydrogels with enzyme-catalyzed semi-inter penetrating polymer network (Semi-IPN) for solar dermatitis
Solar dermatitis is an acute or chronic high incidence of skin injury caused by ultraviolet (UV) radiation based on strong sunlight, which seriously...
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Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma
Cancer therapies often have narrow therapeutic indexes and involve potentially suboptimal combinations due to the dissimilar physical properties of...
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Electrospun PCL scaffold modified with chitosan nanoparticles for enhanced bone regeneration
The encapsulation of ascorbic acid within chitosan nanoparticles (CHNs), embedded in a fibrous structure of a dexamethasone (Dex)-loaded PCL...
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Prodrug-based nanomedicines for rheumatoid arthritis
Most antirheumatic drugs with high toxicity exhibit a narrow therapeutic window due to their nonspecific distribution in the body, leading to...
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