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Shell-sheddable antibiotic nanohybrid through drug-mediated surface-initiated polymerization: an overcoat approach for modulated burst release
AbstractAntibiotic-impregnated bioactive therapeutic biomaterials are highly demanding due to the risk of infection associated with musculoskeletal...
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Composite material consisting of microporous beta-TCP ceramic and alginate-dialdehyde-gelatin for controlled dual release of clindamycin and bone morphogenetic protein 2
The aim of this study was to produce a composite of microporous β-TCP filled with alginate-gelatin crosslinked hydrogel, clindamycin and bone...
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Concentration-dependent bacterial cellulose patches: a strategy for modulating the drug release beyond the modifications of the native cellulose hydrogel
Considering the increasing interest in the need-specific drug release profiles in transdermal patches, the understanding of the complex relationship...
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PEGylated curcumin-loaded nanofibrous mats with controlled burst release through bead knot-on-spring design
APEGylatedcurcumin (PCU) loaded electrospuns based on poly(ε-caprolactone) (PCL) andpolyvinyl alcohol (PVA) were fabricated for wound dressing...
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Clay Hybrids for Sustained-Release Fertilizer
Conventional chemical fertilizers immediately release the majority of their nutrient content after applying it to the soil. Therefore, a significant...
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Temporally controlling the release of biofactors from polymeric microspheres
To improve the integrity of tendons, mitigating scar tissue formation by targeting the cellular activities that contribute to fibrosis during healing...
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Microscale techniques for investigating the chemistry and energy release of reactive materials
Microscale techniques for relatively inexpensive, high-throughput characterization of novel reactive materials using minimal quantities of sample are...
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MRI-based sensing of pH-responsive content release from mesoporous silica nanoparticles
A proof of principle study toward develo** a novel methodology which could be applicable for a non-invasive monitoring of the release of cargo...
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Facile synthesis, characterization, biocompatibility and protein loading/release property of zinc-doped hollow mesoporous bioactive glass nanospheres
We synthetized hollow mesoporous bioactive glass nanospheres (HMBGS) and zinc-doped hollow mesoporous bioactive glass nanospheres (Zn-HMBGS) in which...
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Highly flexible and controllable hierarchical MOF membrane for efficient drug release
An active wound dressing that is biomechanically and biochemically effective is essential for wound care and skin tissue regeneration. Despite its...
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Preparation and release properties of pH-sensitive mesoporous silica composite nanocarriers
To improve the properties of mesoporous silica nanoparticles (MSNs), the surface of MSNs was functionally modified with a pH-sensitive polymer. Using...
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Dexamethasone release from hyaluronic acid microparticle and proanthocyanidin-gelatin hydrogel in sciatic tissue regeneration
Biodegradable microparticles are useful vehicles for the controlled release of bioactive molecules in drug delivery, tissue engineering and...
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Dual gatekeepers-modified dendritic mesoporous silica nanoparticles for controlled drug release
It is urgent to develop functional nanocarriers for targeted drug therapy of cancer. This work developed a smart drug controlled release system based...
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Photothermal switch of drug release from polydopamine-modified nanosheets
Colorectal cancer, which is difficult to treat and has a high recurrence rate, is a challenging target. Here, we propose a novel multi-layered...
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Photothermally modulated drug release kinetics for pH and thermo-responsive hydrogel system
Injectable hydrogel systems to achieve controlled drug release for localized chemotherapy are emerging modality for cancer therapy. Here, an...
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Slow-release fertilizers based on lignin–sodium alginate biopolymeric blend for sustained N–P nutrients release
In this study, biodegradable sodium alginate–lignin (SA-L) blend formulations at different SA/L ratios were developed as low-cost coating material...
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Release of ranibizumab using a porous poly(dimethylsiloxane) capsule suppressed laser-induced choroidal neovascularization via the transscleral route
The administration of anti-vascular endothelial growth factor drugs in the posterior eye segment with sustained release through less invasive methods...
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Controlled release of Clenbuterol from a hydroxyapatite carrier for the treatment of Alzheimer’s Disease
BackgroundAlzheimer’s disease is a neurodegenerative disorder, and Aβ aggregation is considered to be the central process implicated in its...
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Formulation and characterization of polyester-lignite composite coated slow-release fertilizers
Two polyester-lignite composite coated urea slow-release fertilizers (SRFs; Poly3 and Poly5) were developed and their physicochemical properties were...
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Remote loading of minoxidil in nano-reservoirs leads to polymorphism and controlled release
Alopecia, a condition characterized by hair loss leading to baldness, treated with minoxidil, has the side effects of scalp irritation and lowering...
