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1. Protocol variations in run-on transcription dataset preparation produce detectable signatures in sequencing libraries

   Background

   A variety of protocols exist for producing whole genome run-on transcription datasets. However, little is known about how differences...

   Samuel Hunter, Rutendo F. Sigauke, ... Robin D. Dowell in BMC Genomics

   Article Open access 07 March 2022
   

2. Scaling up reproducible research for single-cell transcriptomics using MetaNeighbor

   Single-cell RNA-sequencing data have significantly advanced the characterization of cell-type diversity and composition. However, cell-type...

   Stephan Fischer, Megan Crow, ... Jesse Gillis in Nature Protocols

   Article 07 July 2021
   

3. Why voters who value democracy participate in democratic backsliding

   Around the world, citizens are voting away the democracies they claim to cherish. Here we present evidence that this behaviour is driven in part by...

   Alia Braley, Gabriel S. Lenz, ... Alex Pentland in Nature Human Behaviour

   Article 22 May 2023
   

4. A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus

   Abstract

   Dipeptidyl peptidase-4 (DPP4) is highly participated in regulating diabetes mellitus (DM), and inhibitors of DPP4 may act as potential DM...

   Jia-Ning Gong, Lu Zhao, ... Calvin Yu-Chian Chen in Molecular Diversity

   Article 09 March 2021
   

5. A voting mechanism-based linear epitope prediction system for the host-specific Iridoviridae family

   Background

   The Iridoviridae family is categorized into five genera and clustered into two subfamilies: Alphairidovirinae includes Lymphocystivirus , Ranavirus...

   Tao-Chuan Shih, Li-** Ho, ... Tun-Wen Pai in BMC Bioinformatics

   Article Open access 01 May 2019
   

6. A Member by Any Other Name is…an Alternate?

   Lauren Danridge, Bill Greer in Lab Animal

   Article 29 June 2023

7. Compliance Considerations

   Lauren Danridge, Bill Greer in Lab Animal

   Article 29 June 2023

8. Moral dilemmas and trust in leaders during a global health crisis

   Abstract

   Trust in leaders is central to citizen compliance with public policies. One potential determinant of trust is how leaders resolve conflicts...

   Jim A. C. Everett, Clara Colombatto, ... Molly J. Crockett in Nature Human Behaviour

   Article 01 July 2021
   

9. A practical guide to machine-learning scoring for structure-based virtual screening

   Structure-based virtual screening (SBVS) via docking has been used to discover active molecules for a range of therapeutic targets. Chemical and...

   Viet-Khoa Tran-Nguyen, Muhammad Junaid, ... Pedro J. Ballester in Nature Protocols

   Article 16 October 2023
   

10. Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables

    Background

    Prostate Cancer (PCa) represents the second leading cause of cancer-related death in men. Prostate-specific antigen (PSA) serum testing,...

    Caterina Gabriele, Federica Aracri, ... Marco Gaspari in Clinical Proteomics

    Article Open access 21 November 2023
    

11. A Machine Learning-Based Approach Using Multi-omics Data to Predict Metabolic Pathways

    The integrative method approaches are continuously evolving to provide accurate insights from the data that is received through experimentation on...

    Vidya Niranjan, Akshay Uttarkar, ... Maryanne Varghese in Computational Biology and Machine Learning for Metabolic Engineering and Synthetic Biology

    Protocol 2023
    

12. Insufficient sleep reduces voting and other prosocial behaviours

    Insufficient sleep is a growing public health concern in industrial societies. Although a lack of sleep is known to negatively affect private...

    John B. Holbein, Jerome P. Schafer, David L. Dickinson in Nature Human Behaviour

    Article 04 March 2019
    

13. The potential of DAOs for funding and collaborative development in the life sciences

    Simone Fantaccini, Laura Grassi, Andrea Rampoldi in Nature Biotechnology

    Article 02 April 2024
    

14. Alternate Rights

    Mary Lou James, Laura Lewis in Lab Animal

    Article 29 June 2023

15. Compliance Considerations

    Lauren Danridge, Bill Greer in Lab Animal

    Article 31 July 2023

16. SEVtras delineates small extracellular vesicles at droplet resolution from single-cell transcriptomes

    Small extracellular vesicles (sEVs) are emerging as pivotal players in a wide range of physiological and pathological processes. However, a pressing...

    Ruiqiao He, Junjie Zhu, ... Fangqing Zhao in Nature Methods

    Article Open access 04 December 2023
    

17. Compliance Considerations

    Lauren Danridge, Bill Greer in Lab Animal

    Article 27 July 2022

18. Understanding political divisiveness using online participation data from the 2022 French and Brazilian presidential elections

    Digital technologies can augment civic participation by facilitating the expression of detailed political preferences. Yet, digital participation...

    Carlos Navarrete, Mariana Macedo, ... César A. Hidalgo in Nature Human Behaviour

    Article 16 November 2023
    

19. Planning for the unexpected with DMRs

    Michelle Aparicio in Lab Animal

    Article 27 July 2022

20. Decentralized investor communities gain traction in biotech

    Laura DeFrancesco, Ariel Klevecz in Nature Biotechnology

    Article 30 August 2022