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Three-dimensional morphologic and molecular atlases of nasal vasculature
Understanding the function of the nasal vasculature in homeostasis and pathogenesis of common nasal diseases is important. Here we describe an...
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The extracellular matrix mechanics in the vasculature
Mechanical stimuli from the extracellular matrix (ECM) modulate vascular differentiation, morphogenesis and dysfunction of the vasculature. With...
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Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature
The placenta is a unique organ for ensuring normal embryonic growth in the uterine. Here, we found that maternal RNA transcription in Dlk1-Dio3 ...
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Vasculature cells control neuroglial co-localization and synaptic connection in a central nervous system tissue mimic system
Despite the development of neural tissue differentiation methods using a wide variety of stem cells and compartments, there is no standardized...
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Understanding and Engineering the Pulmonary Vasculature
Blood vessels play essential roles in regulating embryonic organogenesis and adult tissue homeostasis. The inner lining of blood vessels is covered... -
Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease
Population-based association studies have identified many genetic risk loci for coronary artery disease (CAD), but it is often unclear how genes...
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Vasculature atrophy causes a stiffened microenvironment that augments epidermal stem cell differentiation in aged skin
Stem cell loss causes tissue deterioration associated with aging. The accumulation of genomic and oxidative stress-induced DNA damage is an intrinsic...
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ID1high/activin Ahigh glioblastoma cells contribute to resistance to anti-angiogenesis therapy through malformed vasculature
Although bevacizumab (BVZ), a representative drug for anti-angiogenesis therapy (AAT), is used as a first-line treatment for patients with...
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Three-dimensional characterization of develo** and adult ocular vasculature in mice using in toto clearing
The ocular vasculature is critically involved in many blinding diseases and is also a popular research model for the exploration of developmental and...
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Generation of multilineage liver organoids with luminal vasculature and bile ducts from human pluripotent stem cells via modulation of Notch signaling
BackgroundThe generation of liver organoids recapitulating parenchymal and non-parenchymal cell interplay is essential for the precise in vitro...
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Simultaneous induction of vasculature and neuronal network formation on a chip reveals a dynamic interrelationship between cell types
BackgroundNeuronal networks receive and deliver information to regulate bodily functions while the vascular network provides oxygen, nutrients, and...
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The Vasculature in Pulmonary Fibrosis
Purpose of reviewThe current paradigm of idiopathic pulmonary fibrosis (IPF) pathogenesis involves recurrent injury to a sensitive alveolar...
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Ultrasound localization microscopy and functional ultrasound imaging reveal atypical features of the trigeminal ganglion vasculature
The functional imaging within the trigeminal ganglion (TG) is highly challenging due to its small size and deep localization. This study combined a...
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Biochemical and mechanical signals in the lymphatic vasculature
Lymphatic vasculature is an integral part of the cardiovascular system where it maintains interstitial fluid balance. Additionally, lymphatic...
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Computational Assessment of Hemodynamics Vortices Within the Cerebral Vasculature Using Informational Entropy
Propper assessment of hemodynamic swirling flow patterns, vortices, may help understand the influence of disturbed flow on arterial wall... -
Characterization of Lymphatic Vasculature Using Whole-Mount Immunostaining of Mouse Embryonic Dorsal Skin
Understanding the development of the lymphatic vasculature is essential to the understanding of how these vessels function in health and disease.... -
Comparative Transcriptome Profiling Indicated that Leaf Mesophyll and Leaf Vasculature have Different Drought Response Mechanisms in Cassava
Drought stress is one of the major environmental factors that limited crop’s growth and production. Cassava known as a tropical crop that is widely...
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Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels
Cognitive impairment and dementias during aging such as Alzheimer’s disease are linked to functional decline and structural alterations of the brain...
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Early manifestation of aging-related vascular dysfunction in human penile vasculature—A potential explanation for the role of erectile dysfunction as a harbinger of systemic vascular disease
Advanced age is related to functional alterations of human vasculature, but erectile dysfunction precedes systemic manifestations of vascular...
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Quantitative Methods to Assess Adipose Vasculature
Adipose tissue depots are invested with an extensive capillary network that is closely associated with maintenance of adipose functions and enables...