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  1. Droplet-based transcriptome profiling of individual synapses

    Synapses are crucial structures that mediate signal transmission between neurons in complex neural circuits and display considerable morphological...

    Muchun Niu, Wenjian Cao, ... Chenghang Zong in Nature Biotechnology
    Article 16 January 2023
  2. Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers

    Background

    N6-methyladenosine (m6A) is a prevalent and crucial RNA methylation modification that plays a significant role in various biological and...

    Deepa Ramasamy, Megha Thippannah, ... Samson Mani in Molecular Biology Reports
    Article 12 February 2024
  3. Transcriptome Profiling in Experimental Inflammatory Arthritis

    Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects 0.5 to 1% of the human population. Gene expression profiling...
    Olga Martinez Ibañez, José Ricardo Jensen, Marcelo De Franco in Transcriptomics in Health and Disease
    Chapter 2022
  4. Integration of whole transcriptome spatial profiling with protein markers

    Spatial transcriptomics and proteomics provide complementary information that independently transformed our understanding of complex biological...

    Nir Ben-Chetrit, **ang Niu, ... Dan A. Landau in Nature Biotechnology
    Article 02 January 2023
  5. Transcriptome profiling reveals multiple regulatory pathways of Tamarix chinensis in response to salt stress

    Key message

    Multiple regulatory pathways of T . chinensis to salt stress were identified through transcriptome data analysis.

    Abstract

    Tamarix chinensis ...

    Ruxia Li, Rao Fu, ... Hongxia Zhang in Plant Cell Reports
    Article 21 September 2023
  6. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination

    N 6 -methyladenosine (m 6 A), the most abundant internal messenger RNA modification in higher eukaryotes, serves myriad roles in regulating cellular...

    Yu-Lan **ao, Shun Liu, ... Weixin Tang in Nature Biotechnology
    Article 02 January 2023
  7. Transcriptome-Wide Profiling of RNA Stability

    Gene expression is controlled at multiple levels, including RNA transcription and turnover. But determining the relative contributions of RNA...
    Nina Fasching, Jan Petržílek, ... Stefan L. Ameres in Post-Transcriptional Gene Regulation
    Protocol 2022
  8. Transcriptome profiling of two Moringa species and insights into their antihyperglycemic activity

    Background

    Moringa concanensis Nimmo (MC), a plant that resembles Moringa oleifera Lam. (MO), has less scientific information but has traditionally...

    K. Mohamed Shafi, Radha Sivarajan Sajeevan, ... Ramanathan Sowdhamini in BMC Plant Biology
    Article Open access 02 December 2022
  9. Transcriptome analysis in abiotic stress conditions in higher plants

    Drought, high salinity, and low temperature are major environmental factors that limit plant productivity. Plants respond and adapt to these stresses...
    Motoaki Seki, Ayako Kamei, ... Kazuo Shinozaki in Plant Responses to Abiotic Stress
    Chapter
  10. Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens

    We present a combinatorial indexing method, PerturbSci-Kinetics , for capturing whole transcriptomes, nascent transcriptomes and single guide RNA...

    Zihan Xu, Andras Sziraki, ... Junyue Cao in Nature Biotechnology
    Article Open access 25 September 2023
  11. Transcriptome profiling reveals ethylene formation in rice seeds by trichloroisocyanuric acid

    Key message

    Ethylene formation via methionine reacting with trichloroisocyanuric acid under FeSO 4 condition in a non-enzymatical manner provides one...

    Yang Ling, Zhang **shi, ... Zhang Weilin in Plant Cell Reports
    Article 18 August 2023
  12. Transcriptome Profiling in Autoimmune Diseases

    Autoimmune diseases are a group of different inflammatory disorders characterized by systemic or localized inflammation, affecting approximately...
    Cristhianna V. A. Collares, Eduardo A. Donadi in Transcriptomics in Health and Disease
    Chapter 2022
  13. Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks

    Previous studies have suggested that breast cancer (BC) from the Middle East and North Africa (MENA) is presented at younger age with advanced tumor...

    Ramesh Elango, Sameera Rashid, ... Nehad M. Alajez in Cell Death & Disease
    Article Open access 12 July 2023
  14. Simultaneous Single-Cell Profiling of the Transcriptome and Accessible Chromatin Using SHARE-seq

    The ability to analyze the transcriptomic and epigenomic states of individual single cells has in recent years transformed our ability to measure and...
    Samuel H. Kim, Georgi K. Marinov, ... William J. Greenleaf in Chromatin Accessibility
    Protocol 2023
  15. Profiling the polyadenylated transcriptome of extracellular vesicles with long-read nanopore sequencing

    Background

    While numerous studies have described the transcriptomes of extracellular vesicles (EVs) in different cellular contexts, these efforts have...

    Juan-Carlos A. Padilla, Seda Barutcu, ... Eric Lécuyer in BMC Genomics
    Article Open access 22 September 2023
  16. Genome-wide investigation of the LARP gene family: focus on functional identification and transcriptome profiling of ZmLARP6c1 in maize pollen

    Background

    The La-related proteins (LARPs) are a superfamily of RNA-binding proteins associated with regulation of gene expression. Evidence points to...

    **aoqin **ang, Qianxia Deng, ... Lian Zhou in BMC Plant Biology
    Article Open access 29 April 2024
  17. Single-cell profiling reveals transcriptome dynamics during bovine oocyte growth

    Background

    Mammalian follicle development is characterized by extensive changes in morphology, endocrine responsiveness, and function, providing the...

    Lais Barbosa Latorraca, António Galvão, ... Trudee Fair in BMC Genomics
    Article Open access 06 April 2024
  18. Transcriptome profiling of celery petiole tissues reveals peculiarities of the collenchyma cell wall formation

    Main Conclusion

    Transcriptome and biochemical analyses are applied to individual plant cell types to reveal potential players involved in the...

    Natalia Mokshina, Anastasia Panina, ... Polina Mikshina in Planta
    Article 20 December 2022
  19. Transcriptome profiling reveals the impact of various levels of biochar application on the growth of flue-cured tobacco plants

    Background

    Biochar, a carbon-rich source and natural growth stimulant, is usually produced by the pyrolysis of agricultural biomass. It is widely used...

    Yingfen Yang, Waqar Ahmed, ... Zhengxiong Zhao in BMC Plant Biology
    Article Open access 10 July 2024
  20. m6A-SAC-seq for quantitative whole transcriptome m6A profiling

    N 6 -methyladenosine (m 6 A) is the most abundant mRNA modification in mammalian cells, regulating many physiological processes. Here we describe a...

    Ruiqi Ge, Chang Ye, ... Chuan He in Nature Protocols
    Article 25 November 2022
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