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Droplet-based transcriptome profiling of individual synapses
Synapses are crucial structures that mediate signal transmission between neurons in complex neural circuits and display considerable morphological...
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Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers
BackgroundN6-methyladenosine (m6A) is a prevalent and crucial RNA methylation modification that plays a significant role in various biological and...
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Transcriptome Profiling in Experimental Inflammatory Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects 0.5 to 1% of the human population. Gene expression profiling... -
Integration of whole transcriptome spatial profiling with protein markers
Spatial transcriptomics and proteomics provide complementary information that independently transformed our understanding of complex biological...
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Transcriptome profiling reveals multiple regulatory pathways of Tamarix chinensis in response to salt stress
Key messageMultiple regulatory pathways of T . chinensis to salt stress were identified through transcriptome data analysis.
AbstractTamarix chinensis ...
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Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination
N 6 -methyladenosine (m 6 A), the most abundant internal messenger RNA modification in higher eukaryotes, serves myriad roles in regulating cellular...
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Transcriptome-Wide Profiling of RNA Stability
Gene expression is controlled at multiple levels, including RNA transcription and turnover. But determining the relative contributions of RNA... -
Transcriptome profiling of two Moringa species and insights into their antihyperglycemic activity
BackgroundMoringa concanensis Nimmo (MC), a plant that resembles Moringa oleifera Lam. (MO), has less scientific information but has traditionally...
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Transcriptome analysis in abiotic stress conditions in higher plants
Drought, high salinity, and low temperature are major environmental factors that limit plant productivity. Plants respond and adapt to these stresses... -
Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens
We present a combinatorial indexing method, PerturbSci-Kinetics , for capturing whole transcriptomes, nascent transcriptomes and single guide RNA...
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Transcriptome profiling reveals ethylene formation in rice seeds by trichloroisocyanuric acid
Key messageEthylene formation via methionine reacting with trichloroisocyanuric acid under FeSO 4 condition in a non-enzymatical manner provides one...
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Transcriptome Profiling in Autoimmune Diseases
Autoimmune diseases are a group of different inflammatory disorders characterized by systemic or localized inflammation, affecting approximately... -
Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks
Previous studies have suggested that breast cancer (BC) from the Middle East and North Africa (MENA) is presented at younger age with advanced tumor...
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Simultaneous Single-Cell Profiling of the Transcriptome and Accessible Chromatin Using SHARE-seq
The ability to analyze the transcriptomic and epigenomic states of individual single cells has in recent years transformed our ability to measure and... -
Profiling the polyadenylated transcriptome of extracellular vesicles with long-read nanopore sequencing
BackgroundWhile numerous studies have described the transcriptomes of extracellular vesicles (EVs) in different cellular contexts, these efforts have...
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Genome-wide investigation of the LARP gene family: focus on functional identification and transcriptome profiling of ZmLARP6c1 in maize pollen
BackgroundThe La-related proteins (LARPs) are a superfamily of RNA-binding proteins associated with regulation of gene expression. Evidence points to...
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Single-cell profiling reveals transcriptome dynamics during bovine oocyte growth
BackgroundMammalian follicle development is characterized by extensive changes in morphology, endocrine responsiveness, and function, providing the...
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Transcriptome profiling of celery petiole tissues reveals peculiarities of the collenchyma cell wall formation
Main ConclusionTranscriptome and biochemical analyses are applied to individual plant cell types to reveal potential players involved in the...
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Transcriptome profiling reveals the impact of various levels of biochar application on the growth of flue-cured tobacco plants
BackgroundBiochar, a carbon-rich source and natural growth stimulant, is usually produced by the pyrolysis of agricultural biomass. It is widely used...
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m6A-SAC-seq for quantitative whole transcriptome m6A profiling
N 6 -methyladenosine (m 6 A) is the most abundant mRNA modification in mammalian cells, regulating many physiological processes. Here we describe a...