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Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism
Background:Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, reconstructed...
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Characterization and biocompatibility evaluation of acellular rat skin scaffolds for skin tissue engineering applications
Utilization of acellular scaffolds, extracellular matrix (ECM) without cell content, is growing in tissue engineering, due to their high...
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Probiotics for Skin Health
Till now probiotics, live microorganisms with potential health benefits, are popular to maintain gut health, but their potential to keep skin healthy...
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Multi-omics in Study of Skin Microbiome
Skin is the first line of defense of human body against infections where many diverse microbes, including fungi, viruses, bacteria are surviving....
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Skin Drug Administration
The structure of the mouse’s skin is very different from humans; hence, the injection techniques are quite different. Unfortunately, most laboratory...
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Cannabis and the Skin
Anandamide mediates transcriptional effects associated with epidermal differentiation and skin development in those cells through a CB1-dependent...
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Artificial Intelligence Approaches for Skin Anti-aging and Skin Resilience Research
The skin is a complex organ whose functioning is affected by both environmental and intrinsic factors, making it a perfect model for studying the...
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Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway
Skin photoaging is mostly caused by ultraviolet A (UVA), although active medications to effectively counteract UVA-induced photoaging have not yet...
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Skin benefits of postbiotics derived from Micrococcus luteus derived from human skin: an untapped potential for dermatological health
BackgroundThe skin microbiome, a diverse community of microorganisms, plays a crucial role in maintaining skin health. Among these microorganisms,...
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Skin Deep: The Potential of Microbiome Cosmetics
The interplay between the skin microbiome and its host is a complex facet of dermatological health and has become a critical focus in the development...
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Bioengineered skin constructs based on mesenchymal stromal cells and acellular dermal matrix exposed to inflammatory microenvironment releasing growth factors involved in skin repair
BackgroundSkin tissue engineering is a rapidly evolving field of research that effectively combines stem cells and biological scaffolds to replace...
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Cell death as an architect of adult skin stem cell niches
Our skin provides a physical and immunological barrier against dehydration and environmental insults ranging from microbial attacks, toxins and UV...
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Mechanical stiffness promotes skin fibrosis via Piezo1-Wnt2/Wnt11-CCL24 positive feedback loop
Skin fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) caused by fibrotic disorders of the skin. In recent years,...
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Exosomes in skin photoaging: biological functions and therapeutic opportunity
Exosomes are tiny extracellular vesicles secreted by most cell types, which are filled with proteins, lipids, and nucleic acids (non-coding RNAs,...
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Nanoniosomes: Preparation, Characterization, and Insights into the Skin Cancer Therapy (A Review)
AbstractThe skin cancer (mostly of melanoma cells) rate has increased in recent years due to genetic and epigenetic reasons. The efficient treatment...
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Wavelength, dose, skin type and skin model related radical formation in skin
The exposure to sun radiation is indispensable to our health; however, a long-term and high exposure could lead to cell damage, erythema, premature...
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Cellular and molecular mechanisms of skin wound healing
Wound healing is a complex process that involves the coordinated actions of many different tissues and cell lineages. It requires tight orchestration...
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A genome catalog of the early-life human skin microbiome
BackgroundMetagenome-assembled genomes have greatly expanded the reference genomes for skin microbiome. However, the current reference genomes are...
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Mpox virus infection and drug treatment modelled in human skin organoids
Mpox virus (MPXV) primarily infects human skin to cause lesions. Currently, robust models that recapitulate skin infection by MPXV are lacking. Here...
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Targeting lymphoid-derived IL-17 signaling to delay skin aging
Skin aging is characterized by structural and functional changes that contribute to age-associated frailty. This probably depends on synergy between...
