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Short-term fasting of a single amino acid extends lifespan
Diet and health are strongly linked, though the strict changes in diet required to improve health outcomes are usually difficult to sustain. We...
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Prediction of Functional Effects of Protein Amino Acid Mutations
Human Single Amino Acid Polymorphisms (SAPs) or Single Amino Acid Variants (SAVs) usually named as nonsynonymous Single Nucleotide Variants nsSNVs)...
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Amino acid distribution in blood following high-intensity interval exercise: a preliminary study
This study investigated the effect of high-intensity interval exercise on total and individual amino acid concentrations in red blood cells (RBCs)...
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Clustered surface amino acid residues modulate the acid stability of GH10 xylanase in fungi
AbstractAcidic xylanases are widely used in industries such as biofuels, animal feeding, and fruit juice clarification due to their tolerance to...
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Main Factors Sha** Amino Acid Usage Across Evolution
The standard genetic code determines that in most species, including viruses, there are 20 amino acids that are coded by 61 codons, while the other...
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Genetic dissection reveals the complex architecture of amino acid composition in soybean seeds
Key messageFive loci related to soybean protein and amino acid contents were colocated by performing linkage map** and GWAS. The haplotype analysis...
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Detection and Analysis of Amino Acid Insertions and Deletions
Despite being a recurring type of sequence variation, amino acid insertions and deletions InDels), their source and resulting functional significance...
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Pharmacokinetics of L-theanine and the effect on amino acid composition in mice administered with L-theanine
L-theanine, an amino acid component of the tea leaves of Camellia sinensis , is sold in Japan as a supplement for good sleep. Although several studies...
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Analysing postprandial amino acid responses in crossover studies with the aaresponse package for R
Nowadays, a healthier and more sustainable lifestyle is the subject of much research. One example is the use of crossover trials to investigate the...
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StringFix: an annotation-guided transcriptome assembler improves the recovery of amino acid sequences from RNA-Seq reads
BackgroundReconstruction of amino acid sequences from assembled transcriptome is of interest in personalized medicine, for example, to predict...
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Bayesian Cross-Validation Comparison of Amino Acid Replacement Models: Contrasting Profile Mixtures, Pairwise Exchangeabilities, and Gamma-Distributed Rates-Across-Sites
Models of amino acid replacement are central to modern phylogenetic inference, particularly so when dealing with deep evolutionary relationships....
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Amino acid insertion in Bat MHC-I enhances complex stability and augments peptide presentation
Bats serve as reservoirs for numerous zoonotic viruses, yet they typically remain asymptomatic owing to their unique immune system. Of particular...
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Genetic stability, amino acid, and polyamine profile analyses in radiata pine somatic embryos maturated at high temperatures
Applying stress factors such as high temperatures during the different stages of somatic embryogenesis is important to uncover the molecular...
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Effects of the kinetic pattern of dietary glucose release on nitrogen utilization, the portal amino acid profile, and nutrient transporter expression in intestinal enterocytes in piglets
BackgroundPromoting the synchronization of glucose and amino acid release in the digestive tract of pigs could effectively improve dietary nitrogen...
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Natural polymorphism of ZmICE1 contributes to amino acid metabolism that impacts cold tolerance in maize
Cold stress negatively affects maize ( Zea mays L.) growth, development and yield. Metabolic adjustments contribute to the adaptation of maize under...
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Reconstructing herbivore diets: a multivariate statistical approach to interpreting amino acid nitrogen isotope values
Recent studies have demonstrated that there exists significant variability in amino acid (AA) δ 15 N values of terrestrial plants, discriminating among...
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Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study
IntroductionAlzheimer’s Disease (AD) is complex and novel approaches are urgently needed to aid in diagnosis. Blood is frequently used as a source...
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Amino acid utilization allows intestinal dominance of Lactobacillus amylovorus
The mammalian intestine harbors heterogeneous distribution of microbes among which specific taxa (e.g. Lactobacillus ) dominate across mammals....
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Taxonomic, seasonal and spatial variation in the amino acid profile of freshwater macroinvertebrates
Macroinvertebrates play a key role in aquatic food webs, with amino acids (AA) playing an important role in determining their nutritional value to...
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CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns
BackgroundThe placentas from newborns that are small for gestational age (SGA; birth weight < -2 SD for gestational age) may display multiple...
