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A simple and unified protocol to purify all seven Escherichia coli RNA polymerase sigma factors
RNA polymerase sigma factors are indispensable in the process of bacterial transcription. They are responsible for a given gene’s promoter region...
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The modular architecture of sigma factors in cyanobacteria: a framework to assess their diversity and understand their evolution
BackgroundBacterial RNA polymerase holoenzyme requires sigma70 factors to start transcription by identifying promoter elements. Cyanobacteria possess...
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Low-temperature and circadian signals are integrated by the sigma factor SIG5
Chloroplasts are a common feature of plant cells and aspects of their metabolism, including photosynthesis, are influenced by low-temperature...
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Identification of Rhodococcus erythropolis Promoters Controlled by Alternative Sigma Factors Using In Vivo and In Vitro Systems and Heterologous RNA Polymerase
Rhodococcus erythropolis CCM2595 is a bacterial strain, which has been studied for its capability to degrade phenol and other toxic aromatic...
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Cytotoxic sigma-2 ligands trigger cancer cell death via cholesterol-induced-ER-stress
Sigma-2-ligands (S2L) are characterized by high binding affinities to their cognate sigma-2 receptor, overexpressed in rapidly proliferating tumor...
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Role of the sigma factor AlgU in regulating growth, virulence, motility, exopolysaccharide production, and environmental stress adaptation of Pseudomonas syringae pv. actinidiae QSY6
The extracytoplasmic function (ECF) sigma factor AlgU is involved in the regulation of various virulence-related pathways in Pseudomonas syringae ,...
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Multicopy expression of sigma factor RpoH reduces prodigiosin biosynthesis in Serratia marcescens FS14
Regulation of prodigiosin biosynthesis is received wide attention due to the antimicrobial, immunosuppressive and anticancer activities of...
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Distribution of sigma factors delineates segregation of virulent and avirulent Mycobacterium
The genus Mycobacterium includes a wide range of species of both slow and rapid growth under major pathogens, opportunists, and saprophytes. The...
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Extracytoplasmic sigma factor AlgU contributes to fitness of Pseudomonas aeruginosa PGPR2 during corn root colonization
In bacteria, sigma factors are crucial in determining the plasticity of core RNA polymerase (RNAP) while promoter recognition during transcription...
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Role of Sigma-1 Receptors in the Regulation of Heart Function: II. Cardioprotective Role of Sigma-1 Receptors
AbstractPart II of the review considers the literature data that pronounced cardioprotective activity is possessed by sigma-1 receptors (σ 1 Rs) and...
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Sigma Factors of RNA Polymerase in Corynebacterium glutamicum
Corynebacterium glutamicum is an important biotechnological organism as well as a model organism for other corynebacteria including pathogenic... -
Non-Specific Targets for Correction of Pneumonia Caused by Aerosols Containing Damaging Factors of Various Nature
AbstractThis review article provides data on the current state of the pathogenesis peculiarities of body and lung inflammation (pneumonia) under the...
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Role of Sigma-1 Receptors in the Regulation of Heart Function: I. The Structure, Localization, and Functional Activity of Sigma-1 Receptors in Cardiomyocytes
AbstractThe first part of the review examines in detail the structure of sigma-1 (σ1) receptors and the specifics of their intracellular localization...
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Sigma factor binding protein 1 (CsSIB1) is a putative candidate of the major-effect QTL dm5.3 for downy mildew resistance in cucumber (Cucumis sativus)
Key messageThe dm5.3 major-effect QTL in cucumber encodes a homolog of Arabidopsis sigma factor binding protein 1 (CsSIB1). CsSIB1 positively...
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Physiological effects of overexpressed sigma factors on fermentative stress response of Zymomonas mobilis
Zymomonas mobilis is a bacterium of industrial interest due to its high ethanol productivity and high tolerance to stresses. Although the...
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Search for Influence Factors in Lactobacilli with Probiotic Properties Isolated from Traditional Kazakh Foods
The aim of this study was to investigate the factors influencing the probiotic potential of lactobacilli isolated from traditional Kazakh foods,...
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Prokaryotic sigma factors and their transcriptional counterparts in Archaea and Eukarya
RNA polymerases (RNAPs) carry out transcription in the three domains of life, Bacteria , Archaea , and Eukarya . Transcription initiation is highly...
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Evaluation of intrinsic and extrinsic factors affecting pregnancy rate in dual-purpose cows under tropical conditions
Embryo transfer (ET) in bovines was created with the purpose of increasing the pregnancy rate (PR) of animals with high genetic value; however,...
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Role of Heat Shock Factors in Stress-Induced Transcription: An Update
Heat shock proteins (HSP) are rapidly induced after proteotoxic stresses such as heat shock and accumulate at high concentrations in cells. HSP... -
GATA transcription factors drive initial **st upregulation after fertilization through direct activation of long-range enhancers
X-chromosome inactivation (XCI) balances gene expression between the sexes in female mammals. Shortly after fertilization, upregulation of **st RNA...