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Changes of m6A Regulatory Proteins and Nrf2 Signaling Molecules in Liver Tissue of Type 2 Diabetes Mellitus Rats
Both dysregulation of N 6 -methyladenosine (m 6 A) regulatory proteins and Nrf2 signaling molecules are involved in the process of injury to multiple...
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Female baboon adrenal zona fasciculata and zona reticularis regulatory and functional proteins decrease across the life course
Debate exists on life-course adrenocortical zonal function trajectories. Rapid, phasic blood steroid concentration changes, such as circadian rhythms...
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Measuring Proximity-Mediated Function of mRNA Regulatory Proteins by Engineered Tethering
A powerful approach for studying the functional consequences of site-specific RNA–protein interactions is to artificially tether a protein to a...
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Exploring Regulatory Roles of Plant Thylakoid-Bound Proteins Involved in Abiotic Stress Responses
Abiotic stress is triggered by unfavorable environments such as drought, severe heat, heavy metals, soil saturation, high-intensity light, and high...
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Diurnal control of iron responsive element containing mRNAs through iron regulatory proteins IRP1 and IRP2 is mediated by feeding rhythms
BackgroundCellular iron homeostasis is regulated by iron regulatory proteins (IRP1 and IRP2) that sense iron levels (and other metabolic cues) and...
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Regulatory roles of selective autophagy through targeting of native proteins in plant adaptive responses
Key messageSelective autophagy functions as a regulatory mechanism by targeting native and functional proteins to ensure their proper levels and...
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Regulatory Networks
This chapter elaborates on the overview presented in Chapter 3. Gene regulatory networks are complex systems that control the expression of genes in...
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Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana
Deteriorating climatic conditions and increasing human population necessitate the development of robust plant varieties resistant to harsh...
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A Study of the Effect of Glycodelin on the Level of T-Regulatory Lymphocytes and Acute Phase Proteins in Wistar Rats during the Administration of Allogenic Bone Marrow Cells
AbstractThe amniotic variant of glycodelin (GdA) has pronounced immunomodulatory properties, being involved in the formation of immune tolerance...
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Binding Proteins
This chapter pivots to the microscopic world of skeletal muscle-binding proteins—these molecular powerhouses that perform many tasks essential to the...
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Study on the Correlation Between Regulatory Proteins of N6-methyladenosine and Oxidative Damage in Cadmium-induced Renal Injury
As a common environmental heavy metal pollutant, cadmium has been well evidenced to cause kidney damage; yet, the underlying mechanisms are still not...
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Inferring upstream regulatory genes of FOXP3 in human regulatory T cells from time-series transcriptomic data
The discovery of upstream regulatory genes of a gene of interest still remains challenging. Here we applied a scalable computational method to...
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Large-scale phosphoproteome analysis in wheat seedling leaves provides evidence for extensive phosphorylation of regulatory proteins during CWMV infection
BackgroundChinese wheat mosaic virus (CWMV) often causes severe damage to wheat ( Triticum aestivum L.) growth and yield. It is well known that a...
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A comparative meta-proteomic pipeline for the identification of plasmodesmata proteins and regulatory conditions in diverse plant species
BackgroundA major route for cell-to-cell signalling in plants is mediated by cell wall-embedded pores termed plasmodesmata forming the symplasm....
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Sex Differences in Age-Related Changes in Functional Activity and Expression of the Main Regulatory Proteins of the Renin–Angiotensin System in the Aorta and Myocardium of Rats
AbstractThe sex differences of age-related changes in the functional activity and expression of receptor and regulatory proteins of the...
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Map** of the plant SnRK1 kinase signalling network reveals a key regulatory role for the class II T6P synthase-like proteins
The central metabolic regulator SnRK1 controls plant growth and survival upon activation by energy depletion, but detailed molecular insight into its...
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Tubby-like proteins (TLPs) transcription factor in different regulatory mechanism in plants: a review
Tubby-like proteins (TLPs) transcription factors are found in single-celled to multi-cellular eukaryotes in the form of large multigene families....
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Regulatory Non-Coding RNAs in Crops Health and Disease
AbstractFor many years it was thought that the function of RNA was limited to the process of producing proteins. In recent years, scientific...
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Production of Pharmaceutical Proteins in Genetically Modified Seeds
In the last few decades, with the progress of plant genetic engineering, the use of plants as bioreactors has emerged as a promising alternative in...
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Genome-Wide Identification, In Silico Characterization of AtCOP1-Targeting Regulatory Proteins Network and their Expression Profiling in The COP1 Downregulated Arabidopsis thaliana
The functional diversification of the RING-finger constitutive photomorphogenesis 1 (COP1) enzyme highly depends on its (in)direct interaction with...
