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S‑Glutathionylation and S‑Nitrosylation as Modulators of Redox-Dependent Processes in Cancer Cell
AbstractDevelopment of oxidative/nitrosative stress associated with the activation of oncogenic pathways results from the increase in the generation...
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Fundamentals of redox regulation in biology
Oxidation–reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of...
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Thiol Redox Proteomics for Identifying Redox-Sensitive Cysteine Residues Within the Protein of Interest During Stress
Redox modulation is a common posttranslational modification to regulate protein activity. The targets of oxidizing agents are cysteine...
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Redox signaling and modulation in ageing
In spite of considerable progress that has been reached in understanding how reactive oxygen species (ROS) interact with its cellular targets,...
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Methacrylate Redox Systems of Anaerobic Bacteria
This review analyzes current information about the anaerobic type of respiration using a synthetic methacrylate compound as an electron acceptor....
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Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence
The fungal pathogen Cryptococcus neoformans is well adapted to its host environment. It has several defence mechanisms to evade oxidative and...
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Gastrointestinal redox homeostasis in ageing
The gastrointestinal (GI) barrier acts as the primary interface between humans and the external environment. It constantly faces the risk of...
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Exploring redox imbalance and inflammation for asthma therapy
Background:Asthma is a prolonged inflammatory disorder of the airways, that affects an estimated 300 million people worldwide. Asthma is triggered by...
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Dynamics of redox signaling in aging via autophagy, inflammation, and senescence
Review paper attempts to explain the dynamic aspects of redox signaling in aging through autophagy, inflammation, and senescence. It begins with ROS...
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Neuronal Calcium Sensor-1: A Zinc/Redox-Dependent Protein of Nervous System Signaling Pathways
AbstractIntracellular calcium signaling is involved in regulating the key functional mechanisms of the nervous system. The control of neuronal...
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Redox signaling in impaired cascades of wound healing: promising approach
In the aging communities, wound healing management is a quite remarkable problem especially in elderly individuals. The optimal level of healing of...
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Phylogenetic conservation of the interdependent homeostatic relationship of sleep regulation and redox metabolism
Sleep is an essential and evolutionarily conserved process that affects many biological functions that are also strongly regulated by cellular...
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Cytochrome bd as Antioxidant Redox Enzyme
AbstractOne of the main functions of enzyme complexes that constitute electron transport (respiratory) chains of organisms is to maintain cellular...
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Redox controls on anaerobic ammonium oxidation coupled to reduction of natural organic matter in paddy ecosystems
Microbially mediated anaerobic ammonium oxidation can be coupled to the reduction of various terminal electron acceptors. Redox-active natural...
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Ethylene Synthesis and Redox Homeostasis in Plants: Recent Advancement
The life cycle of plants is regulated by ethylene in numerous ways, including adaptations to biotic and abiotic stimuli, flower growth, fruit...
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Processes in submerged soils – linking redox potential, soil organic matter turnover and plants to nutrient cycling
BackgroundSubmerged soils are globally important both in natural and agricultural ecosystems and cover 5–7% of the global land surface. Therefore,...
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RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth
NADH/NAD + redox balance is pivotal for cellular metabolism. Systematic identification of NAD(H) redox regulators, although currently lacking, would...
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Redox regulation of UPR signalling and mitochondrial ER contact sites
Mitochondria and the endoplasmic reticulum (ER) have a synergistic relationship and are key regulatory hubs in maintaining cell homeostasis....
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Redox potential as a soil health indicator – how does it compare to microbial activity and soil structure?
Background and aimsRedox potential is a promising soil health indicator, which integrates the combined effect of chemical oxidation–reduction...
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Super-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma
Osteosarcoma (OS) is a common type of bone tumor for which there has been limited therapeutic progress over the past three decades. The prevalence of...
