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Flash entropy search to query all mass spectral libraries in real time
Public repositories of metabolomics mass spectra encompass more than 1 billion entries. With open search, dot product or entropy similarity,...
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MetageNN: a memory-efficient neural network taxonomic classifier robust to sequencing errors and missing genomes
BackgroundWith the rapid increase in throughput of long-read sequencing technologies, recent studies have explored their potential for taxonomic...
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HESML: a real-time semantic measures library for the biomedical domain with a reproducible survey
BackgroundOntology-based semantic similarity measures based on SNOMED-CT, MeSH, and Gene Ontology are being extensively used in many applications in...
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Multi-night acoustic stimulation is associated with better sleep, amyloid dynamics, and memory in older adults with cognitive impairment
Sleep is a potential early, modifiable risk factor for cognitive decline and dementia. Impaired slow wave sleep (SWS) is pronounced in individuals...
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The Blursday database as a resource to study subjective temporalities during COVID-19
The COVID-19 pandemic and associated lockdowns triggered worldwide changes in the daily routines of human experience. The Blursday database provides...
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aMeta: an accurate and memory-efficient ancient metagenomic profiling workflow
Analysis of microbial data from archaeological samples is a growing field with great potential for understanding ancient environments, lifestyles,...
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BoardION: real-time monitoring of Oxford Nanopore sequencing instruments
BackgroundOne of the main advantages of the Oxford Nanopore Technology (ONT) is the possibility of real-time sequencing. This gives access to...
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Memory reactivation in slow wave sleep enhances relational learning in humans
Sleep boosts the integration of memories, and can thus facilitate relational learning. This benefit may be due to memory reactivation during non-REM...
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Hybrid deep learning model for in-field pest detection on real-time field monitoring
The growth of important crops in agriculture can be affected and the production is reduced due to various pest attacks. The detection and recognition...
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Long-term, multi-event surprise correlates with enhanced autobiographical memory
Neurobiological and psychological models of learning emphasize the importance of prediction errors (surprises) for memory formation. This...
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ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis
Memory CD8 + T cells play a crucial role in infection and cancer and mount rapid responses to repeat antigen exposure. Although memory cell...
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Spatial memory predicts home range size and predation risk in pheasants
Most animals confine their activities to a discrete home range, long assumed to reflect the fitness benefits of obtaining spatial knowledge about the...
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The effect of prediction error on episodic memory encoding is modulated by the outcome of the predictions
Expectations can lead to prediction errors of varying degrees depending on the extent to which the information encountered in the environment...
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A novel TF molecular switch-mechanism found in two contrasting ecotypes of a psammophyte, Agriophyllum squarrosum, in regulating transcriptional drought memory
BackgroundPrior drought stress may change plants response patterns and subsequently increase their tolerance to the same condition, which can be...
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Aging: working memory capacity and spatial strategies in a virtual orientation task
Brain networks involved in working and spatial memory are closely intertwined, outlining a potential relation between these processes, which are also...
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Research on wind pressure characteristics of traditional timber buildings: a case study of the main hall of Shisi Temple
Traditional timber buildings are sensitive to wind action. Studying the wind pressure characteristics is the premise for the preventive conservation...
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High-Performance Computing Strategy Using Distributed-Memory Supercomputers
Database peptide search is the most commonly employed computational technique to deduce peptides from the experimentally obtained mass spectrometry...
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BDDBlast—A Memory Efficient Architecture for Pairwise Alignments
BLAST, or Basic Local Alignment Search Tool, is one of the most widely used bioinformatics tools today. However, as biological data accumulates, its...
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Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodeling and Xbp1
A transient, homeostatic transcriptional response can result in transcriptional memory, programming subsequent transcriptional outputs....
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PhyloSophos: a high-throughput scientific name map** algorithm augmented with explicit consideration of taxonomic science, and its application on natural product (NP) occurrence database processing
BackgroundThe standardization of biological data using unique identifiers is vital for seamless data integration, comprehensive interpretation, and...
