Search
Search Results
-
Decellularized Prostate for Cancer Studies
AbstractRegenerative medicine researchers are interested in extracellular matrix (ECM) investigations around fabricating scaffolds that mimic the...
-
Recent advances in flavonoid compounds for the treatment of prostate cancer
Prostate cancer is a malignant epithelial tumor of the prostate gland and is the most common malignant tumor of the male genitourinary system....
-
Targeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth
Sphingosine kinases (SphK), including SphK1 and SphK2, are important enzymes promoting progression of prostate cancer. SKI-178 is a novel and highly...
-
The “Ins and Outs” of Prostate Specific Membrane Antigen (PSMA) as Specific Target in Prostate Cancer Therapy
Prostate-specific membrane antigen (PSMA)PSMA is expressed in epithelial cells of the prostate gland and is strongly upregulated in prostatic...
-
Identification of the mitochondrial protein POLRMT as a potential therapeutic target of prostate cancer
RNA polymerase mitochondria (POLRMT) is essential for mitochondrial transcription machinery and other mitochondrial functions. Its expression and...
-
UBE2N promotes cell viability and glycolysis by promoting Axin1 ubiquitination in prostate cancer cells
BackgroundUbiquitin-conjugating enzyme E2 N (UBE2N) is recognized in the progression of some cancers; however, little research has been conducted to...
-
8-Br-cGMP activates HSPB6 and increases the antineoplastic activity of quinidine in prostate cancer
Heat shock protein family B [small] member 6 (HSPB6), widely found in various muscles, has been recently identified as a tumor suppressor gene....
-
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway
Aberrant activation of the PI3K/AKT pathway is a driving factor in the development of prostate cancer. Therefore, inhibiting the function of the...
-
Interaction of pRb and β-Catenin in Cancer and Normal Human Prostate Tissue
AbstractProstate cancer (PCa) is one of the most common oncological diseases, which passes through two stages in its development: localized PCa and...
-
Inhibition of CDKL3 downregulates STAT1 thus suppressing prostate cancer development
Prostate cancer poses a great threat to men’s health worldwide, yet its treatment is still limited by the unclear understanding of its molecular...
-
A novel circular RNA, circMAML3, promotes tumor progression of prostate cancer by regulating miR-665/MAPK8IP2 axis
Many studies have now demonstrated that circRNAs are aberrantly expressed in cancer and are involved in the regulation of malignant tumor...
-
Ferroptosis landscape in prostate cancer from molecular and metabolic perspective
Prostate cancer is a major disease that threatens men’s health. Its rapid progression, easy metastasis, and late castration resistance have brought...
-
Cuproptosis Regulates Microenvironment and Affects Prognosis in Prostate Cancer
Current immunotherapy for prostate cancer is still in the stage of clinical trials. This delay is thought to be caused by an unclear regulatory...
-
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer
Tumor expression of prostate-specific membrane antigen (PSMA) is lost in 15–20% of men with castration-resistant prostate cancer (CRPC), yet the...
-
Fluorescent Conjugates Based on Prostate-Specific Membrane Antigen Ligands as an Effective Visualization Tool for Prostate Cancer
AbstractFluorescent dyes are widely used in histological studies and in intraoperative imaging, including surgical treatment of prostate cancer (PC),...
-
Bacterial Peptides and Bacteriocins as Novel Treatment for Prostate Cancer
Prostate cancer is well known as the most diagnostic urinary system tumor in the male population. The most conventional cancer therapy is surgery,...
-
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2
Treatment-induced neuroendocrine prostate cancer (t-NEPC) is a lethal subtype of castration-resistant prostate cancer resistant to androgen receptor...
-
B7-H3 specific CAR-T cells exhibit potent activity against prostate cancer
B7-H3 is an attractive target for immunotherapy because of its high expression across multiple solid tumors, including prostate cancer, and...
-
Knockdown of KIF15 suppresses proliferation of prostate cancer cells and induces apoptosis through PI3K/Akt signaling pathway
Prostate cancer is one of the most common malignancies in men, which has been considered a public health threat. KIF15 is a kind of driver protein,...
-
Computational Analysis of Differentially Expressed Circulating MicroRNA and Identification of Key Genes in Prostate Cancer
Bioinformatics is considered a powerful tool to investigate and deeply analyze large datasets. A significant quantity of data is generated by...
