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Ultrasonic technologies in imaging and drug delivery
Ultrasonic technologies show great promise for diagnostic imaging and drug delivery in theranostic applications. The development of functional and...
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Understanding plant pathogen interactions using spatial and single-cell technologies
Plants are in contact with diverse pathogens and microorganisms. Intense investigation over the last 30 years has resulted in the identification of...
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Single-cell proteomics enabled by next-generation sequencing or mass spectrometry
In the last decade, single-cell RNA sequencing routinely performed on large numbers of single cells has greatly advanced our understanding of the...
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Uncovering biology by single-cell proteomics
Recent technological advances have opened the door to single-cell proteomics that can answer key biological questions regarding how protein...
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Identification of the lateral organ boundary domain gene family and its preservation by exogenous salicylic acid in Cerasus humilis
The gene family known as the Lateral Organ Boundary Domain ( LBD ) is responsible for producing transcription factors unique to plants, which play a...
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Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model
BackgroundSporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is a fatal neurodegenerative disease with currently no...
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DNA oder das Buch des Lebens
Über DNA ist schon so einiges geschrieben worden. Vieles davon kann man in Lehrbüchern der Genetik nachlesen. Hier beleuchten wir, was DNA so einzig...
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Precise Chip-to-Chip Reagent Transfer for Cross-Reactivity-Free Multiplex Sandwich Immunoassays
Common multiplex sandwich immunoassays suffer from cross-reactivity due to the mixing of detection antibodies and the combinatorial, undesired...
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Antimicrobial and anti-aflatoxigenic activities of nanoemulsions based on Achillea millefolium and Crocus sativus flower extracts as green promising agents for food preservatives
BackgroundAlthough the mechanism of action of nanoemulsion is still unclear, the modern use of nanoemulsions made from natural extracts as...
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Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
The human immunodeficiency virus epidemic continues in sub-Saharan Africa, and particularly affects adolescent girls and women who have limited...
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Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data
High-throughput single-cell RNA-seq (scRNA-seq) is a powerful tool for studying gene expression in single cells. Most current scRNA-seq...
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scPROTEIN: a versatile deep graph contrastive learning framework for single-cell proteomics embedding
Single-cell proteomics sequencing technology sheds light on protein–protein interactions, posttranslational modifications and proteoform dynamics in...
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Single Cell Proteogenomics — Immediate Prospects
Recent technical advances in genomic technology have led to the explosive growth of transcriptome-wide studies at the level of single cells. The...
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Cassia species: a potential source of biopesticides
Climate change is of significant concern for crop production as it affects crop pests and disease susceptibility, thus affecting crop health and...
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The emerging landscape of single-molecule protein sequencing technologies
Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be...
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Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation
Although the development of hematopoietic stem cells (HSC) has been studied in great detail, their heterogeneity and relationships to different cell...
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Recent advances in proteomics and metabolomics in plants
Over the past decade, systems biology and plant-omics have increasingly become the main stream in plant biology research. New developments in mass...
