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1. Differential Expression of Circulating miR-221-3p, miR-146a-5p, miR-206 and Their Diagnostic Value in Lung Cancer

   Lung cancer is a major health problem and the second most common cancer in the Kashmiri population. It is often diagnosed at an advanced stage,...

   Javaid Ahmed Wani, Sabhiya Majid, ... Heena shafi in Indian Journal of Clinical Biochemistry

   Article 13 April 2024
   

2. Exosomes Derived from Adipose Stem Cells Enhance Angiogenesis in Diabetic Wound Via miR-146a-5p/JAZF1 Axis

   Chronic trauma in diabetes is a leading cause of disability and mortality. Exosomes show promise in tissue regeneration. This study investigates the...

   Dehui Che, **njian **ang, ... Dongsheng Cao in Stem Cell Reviews and Reports

   Article Open access 23 February 2024
   

3. Hepatocyte-derived exosomal miR-146a-5p inhibits hepatic stellate cell EMT process: a crosstalk between hepatocytes and hepatic stellate cells

   Recently, Salidroside (Sal) has been demonstrated to suppress hepatic stellate cell (HSC) activation, a crucial event for liver fibrosis. Moreover,...

   Zhichao Lang, Yifei Li, ... Jianjian Zheng in Cell Death Discovery

   Article Open access 19 August 2023
   

4. MiR-146a-5p delivered by hucMSC extracellular vesicles modulates the inflammatory response to sulfur mustard-induced acute lung injury

   Background

   Sulfur mustard (SM) is a highly toxic chemical warfare agent that has caused numerous casualties during wars and conflicts in the past...

   Zhipeng Pei, **feng Cen, ... Kai **ao in Stem Cell Research & Therapy

   Article Open access 30 May 2023
   

5. MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway

   Glioma-associated macrophages (GAMs) are pivotal chains in the tumor immune microenvironment (TIME). GAMs mostly display M2-like phenotypes with...

   Chao Xu, Pan Wang, ... Nan Wu in Cell Death Discovery

   Article Open access 30 June 2023
   

6. Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts

   C-X-C motif chemokine receptor 7 (CXCR7) is a newly discovered atypical chemokine receptor that binds to C-X-C motif chemokine ligand 12 (CXCL12)...

   Dong Wang, **aohui Wang, ... **nfeng Yu in Cell Death & Disease

   Article Open access 20 April 2022
   

7. miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

   Background

   Acute spinal cord injury (SCI) is a devastating result of neurological trauma with subsequent microenvironment dyshomeostasis that induces...

   Xunwei Lai, Yang Wang, ... Limin Rong in Stem Cell Research & Therapy

   Article Open access 30 September 2022
   

8. MiR-146a-5p, targeting ErbB4, promotes 3T3-L1 preadipocyte differentiation through the ERK1/2/PPAR-γ signaling pathway

   Background

   MicroRNAs (MiRNAs) are known to participate in preadipocyte differentiation, but the manner in which miR-146a-5p participates in this...

   Yifen Wang, Jie Zhang, ... Shousheng Liu in Lipids in Health and Disease

   Article Open access 15 June 2022
   

9. miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia

   Objective

   This study aims to identify the effect of miR-146a-5p on trophoblast cell invasion as well as the mechanism in preeclampsia (PE).

   ...

   **** Peng, Huamei Song, ... Jufang Qin in Biological Research

   Article Open access 13 September 2021
   

10. Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway

    Background

    Bone marrow cells (BMCs), especially mesenchymal stem cells (MSCs), have shown attractive application prospects in acute myocardial...

    Yuyan **ong, Ruijie Tang, ... Yue** Yang in Stem Cell Research & Therapy

    Article Open access 07 July 2022
    

11. miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes

    MicroRNAs (miRNAs) are potent regulators of multiple biological processes. Previous studies have demonstrated that miR-146a-5p increases in normal...

    Allancer D. C. Nunes, Moritz Weigl, ... Michal M. Masternak in GeroScience

    Article 25 November 2021
    

12. Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis

    Bone marrow mesenchymal stem cells (BMSCs) are associated with immune thrombocytopenia (ITP), the underlying mechanism has not been fully elucidated....

    Yue He, Dexiang Ji, ... Guoan Chen in Human Cell

    Article 30 May 2021
    

13. Extracellular vesicles containing miR-146a-5p secreted by bone marrow mesenchymal cells activate hepatocytic progenitors in regenerating rat livers

    Background

    Small hepatocyte-like progenitor cells (SHPCs) appear to form transient clusters in rat livers treated with retrorsine (Ret) and 70%...

    Norihisa Ichinohe, Masayuki Ishii, ... Toshihiro Mitaka in Stem Cell Research & Therapy

    Article Open access 29 May 2021
    

14. MiR-146a-5p targeting SMAD4 and TRAF6 inhibits adipogenensis through TGF-β and AKT/mTORC1 signal pathways in porcine intramuscular preadipocytes

    Background

    Intramuscular fat (IMF) content is a vital parameter for assessing pork quality. Increasing evidence has shown that microRNAs (miRNAs) play...

    Que Zhang, Rui Cai, ... Weijun Pang in Journal of Animal Science and Biotechnology

    Article Open access 03 February 2021
    

15. miR-146a-5p impairs melanoma resistance to kinase inhibitors by targeting COX2 and regulating NFkB-mediated inflammatory mediators

    Background

    Targeted therapy with BRAF and MEK inhibitors has improved the survival of patients with BRAF-mutated metastatic melanoma, but most...

    Elisabetta Vergani, Matteo Dugo, ... Viviana Vallacchi in Cell Communication and Signaling

    Article Open access 23 September 2020
    

16. Microglial exosomes alleviate intermittent hypoxia-induced cognitive deficits by suppressing NLRP3 inflammasome

    Intermittent hypoxia is the best predictor of develo** cognitive decline and Alzheimer’s disease progression in patients with obstructive sleep...

    Yaodan Zhang, Yuyang Miao, ... Qiang Zhang in Biology Direct

    Article Open access 13 June 2023
    

17. MicroRNA -21 expression as an auxiliary diagnostic biomarker of acute brucellosis

    Background

    This study aimed to measure the expression levels of peripheral blood miRNAs in brucellosis and their involvement in the different phases...

    Mahsa Rezaeepoor, Fariba Keramat, ... Ghasem Solgi in Molecular Biology Reports

    Article 01 February 2024
    

18. miRNAs in treatment-resistant depression: a systematic review

    Background

    Treatment-resistant depression (TRD) is a condition in a subset of depressed patients characterized by resistance to antidepressant...

    Lun Cai, **gwen Xu, ... Li** Wei in Molecular Biology Reports

    Article 10 May 2024
    

19. Novel roles of LSECtin in gastric cancer cell adhesion, migration, invasion, and lymphatic metastasis

    Liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin) plays an important regulatory role in a variety of diseases, including...

    Yinan Zhang, Zhen Feng, ... Shuangyi Ren in Cell Death & Disease

    Article Open access 11 July 2022
    

20. HucMSC exosomes promoted imatinib-induced apoptosis in K562-R cells via a miR-145a-5p/USP6/GLS1 axis

    Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm with increasing incidence worldwide. Growing evidence suggests that...

    **aowen Chen, Yixin Chen, ... Feiqiu Wen in Cell Death & Disease

    Article Open access 28 January 2022