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Probing chromatin condensation dynamics in live cells using interferometric scattering correlation spectroscopy
Chromatin organization and dynamics play important roles in governing the regulation of nuclear processes of biological cells. However, due to the...
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Volumetric interferometric lattice light-sheet imaging
Live cell imaging with high spatiotemporal resolution and high detection sensitivity facilitates the study of the dynamics of cellular structure and...
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Acoustofluidic interferometric device for rapid single-cell physical phenoty**
High-throughput single-cell analysis based on physical properties (such as morphology or mechanics) is emerging as a powerful tool to inform clinical...
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Enhancing the precision limits of interferometric satellite geodesy missions
Satellite geodesy uses the measurement of the motion of one or more satellites to infer precise information about the Earth’s gravitational field. In...
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High-Resolution Tracking of Dynein-Dynactin-BicD2 Complexes
The adapter dynactin and the activator BicD2 associate with dynein to form the highly motile dynein-dynactin-BicD2 (DDB) complex. In single-molecule...
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Non-destructive inspection and quantification of defects in plywood using a portable digital holographic camera
The demand for plywood products for the interior and exterior construction has grown significantly over the years. Therefore, detection of defects...
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Precision size and refractive index analysis of weakly scattering nanoparticles in polydispersions
Characterization of the size and material properties of particles in liquid suspensions is in very high demand, for example, in the analysis of...
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DNA-Protein Interactions Studied Directly Using iSCAT Imaging of GNP-Tagged Proteins
Many protein interactions with DNA are reliant on the presence of specific DNA sequences, adducts, or structures. In bulk-phase experiments such DNA...
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Self-supervised machine learning pushes the sensitivity limit in label-free detection of single proteins below 10 kDa
Interferometric scattering (iSCAT) microscopy is a label-free optical method capable of detecting single proteins, localizing their binding positions...
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Mass-sensitive particle tracking to elucidate the membrane-associated MinDE reaction cycle
In spite of their great importance in biology, methods providing access to spontaneous molecular interactions with and on biological membranes have...
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Optical interferometry based micropipette aspiration provides real-time sub-nanometer spatial resolution
Micropipette aspiration (MPA) is an essential tool in mechanobiology; however, its potential is far from fully exploited. The traditional MPA...
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Deep learning-based image enhancement in optical coherence tomography by exploiting interference fringe
Optical coherence tomography (OCT), an interferometric imaging technique, provides non-invasive, high-speed, high-sensitive volumetric biological...
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Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding
BackgroundLysophosphatidic acid ( LPA ) is a bioactive lysophospholipid that acts through its six cognate G protein-coupled receptors. As a family,...
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Artificial intelligence-enabled quantitative phase imaging methods for life sciences
Quantitative phase imaging, integrated with artificial intelligence, allows for the rapid and label-free investigation of the physiology and...
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Enhanced 4Pi single-molecule localization microscopy with coherent pupil based localization
Over the last decades, super-resolution techniques have revolutionized the field of fluorescence microscopy. Among them, interferometric or 4Pi...
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Average Rheological Quantities of Cells in Monolayers
The method of cell monolayer rheology enables quantifying average rheological properties of cell in a single experimental run of few millions cells...
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A way forward for fundamental physics in space
Space-based research can provide a major leap forward in the study of key open questions in the fundamental physics domain. They include the validity...
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Estimating Aboveground Forest Biomass Using Radar Methods
AbstractThe forest biomass dynamics in boreal forests has a significant effect on global carbon cycles. Biomass estimates provide insight into the...
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