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Distribution, shape, and immunohistochemical characteristics of serotonin-immunoreactive neuroendocrine cells in the urethra and periurethral genital organs in mice
The aim of this study is to clarify the disibution, shape, and immunohistochemical characteristics of serotonin-immunoreactive neuroendocrine cells...
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Immunoreactive peptide maps of SARS-CoV-2
Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity among the human coronaviruses (HCoVs): SARS-CoV-2, SARS-CoV-1,...
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Immunoreactive Proteins of Dormant Mycobacterium tuberculosis Cells
AbstractThe protein profile of dormant Mtb obtained after the gradual acidification of Mtb culture was studied to find antigenic proteins for humans...
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Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage
Nucleolar protein 12 (NOL12), one of the nucleolar proteins which are primarily expressed in the nucleolus and play key roles in RNA metabolism, cell...
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Mini-Bioreactor Platform for Membrane Protein Production in Komagataella pastoris
Membrane proteins (MPs) play vital roles across various cellular functions, biological processes, physiological signaling pathways, and human-related...
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Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
BackgroundAcute respiratory distress syndrome (ARDS) is a disease with high mortality and morbidity. Regulator of G protein signaling protein 6...
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Gap Junction Protein Connexin-43 in a Rat Dorsal Root Ganglion
AbstractThe study aimed at investigating the dynamics of the distribution and localization of the gap junction protein connexin-43 (Cx43) in rat...
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Protein secretion and associated stress in industrially employed filamentous fungi
AbstractApplication of filamentous fungi for the production of commercial enzymes such as amylase, cellulase, or xylanase is on the rise due to the...
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The Chaperone Protein Cct5 is Essential for Hematopoietic Stem Cell Maintenance
Proper proteostasis is indispensable for the long-term maintenance of hematopoietic stem and progenitor cells (HSPCs). The TRiC/CCT...
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Biochemical and subcellular characterization of a squid hnRNPA/B-like protein 2 in osmotic stress activated cells reflects molecular properties conserved in this protein family
BackgroundWe have identified endogenous p65 to be an SDS-stable dimer protein composed of ~ 37 kDa hnRNPA/B-like subunits. We have investigated...
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USP14 deficiency inhibits neointima formation following vascular injury via degradation of Skp2 protein
Ubiquitin-proteasome system (UPS) is involved in vascular smooth muscle cell (VSMC) proliferation. Deubiquitinating enzymes (DUBs) have an essential...
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SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA
Human single-stranded DNA-binding protein homologs hSSB1 (SOSSB1) and hSSB2 (SOSSB2) make a vital impact on maintaining genome stability as the B...
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Epitope Map** on Microarrays Highlights a Sequence on the N Protein with Strong Immune Response in SARS-CoV-2 Patients
In SARS-CoV-2 pandemic scenario, the identification of rapid methods to detect antibodies against coronavirus has been a wide and urgent issue....
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Production of recombinant human long-acting IL-18 binding protein: inhibitory effect on ulcerative colitis in mice
AbstractInterleukin-18 binding protein (IL-18BP) is a natural IL-18 inhibitor in vivo , which can effectively neutralize IL-18 and inhibit the...
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The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease
A CAG repeat sequence in the ATXN2 gene encodes a polyglutamine (polyQ) tract within the ataxin-2 (ATXN2) protein, showcasing a complex landscape of...
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CircMIB2 therapy can effectively treat pathogenic infection by encoding a novel protein
The mRNA therapy is widely used in the treatment of diseases due to its efficient characteristics, and the COVID-19 vaccine is the application of...
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Chronic Starvation-Induced Alterations in Biochemical Parameters and Hypothalamic-Pituitary-Testicular Axis in the Mozambique Tilapia Oreochromis mossambicus (Cichlidae)
AbstractAlthough fish are often exposed to food restrictions in natural or aquafarming conditions, the relationship between altered energy status and...
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Co-fractionation–mass spectrometry to characterize native mitochondrial protein assemblies in mammalian neurons and brain
Human mitochondrial (mt) protein assemblies are vital for neuronal and brain function, and their alteration contributes to many human disorders,...
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GFAP- and Vimentin-Immunopositive Structures in Human Pineal Gland
AbstractThe pineal gland plays a key role in coordinating various bodily functions. The majority of pineal cells are pinealocytes, and the second...
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Structural insights into regulation of CCN protein activities and functions
CCN proteins play important functions during development, in repair mechanisms following tissue injury, as well as in pathophysiologic mechanisms of...
