Search
Search Results
-
Immunobiology of cancer stem cells and their immunoevasion mechanisms
Cancer stem cells (CSCs) defined as a small fraction of cells within malignancies have been isolated from tumors with different histological origins...
-
The immunobiology and clinical use of genetically engineered porcine hearts for cardiac xenotransplantation
A summary of the scientific rationale of the advancements that led to the first genetically modified pig-to-human cardiac xenotransplantation is...
-
Reverse Genetics Applied to Immunobiology of Tumor Necrosis Factor, a Multifunctional Cytokine
AbstractTumor necrosis factor (TNF) is one of many cytokines – protein molecules responsible for communication between the cells of immune system....
-
The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia
The immune responses to cancer cells involve both innate and acquired immune cells. In the meantime, the most attention has been drawn to the...
-
Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment
T cell-centric immunotherapies have shown modest clinical benefit thus far for estrogen receptor-positive (ER + ) breast cancer. Despite accounting for...
-
Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines
Rhesus cytomegalovirus (RhCMV)-based vaccination against Simian Immunodeficiency virus (SIV) elicits MHC-E-restricted CD8+ T cells that stringently...
-
IL-17 Triggers Invasive and Migratory Properties in Human MSCs, while IFNy Favors their Immunosuppressive Capabilities: Implications for the “Licensing” Process
Mesenchymal stromal cells (MSCs) were first used as a source for cell therapy in 1995; however, despite their versatility and unambiguous...
-
ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network
BackgroundWhile technological advances have made it possible to profile the immune system at high resolution, translating high-throughput data into...
-
Arginine-dependent immune responses
A growing body of evidence indicates that, over the course of evolution of the immune system, arginine has been selected as a node for the regulation...
-
-
-
Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish
The stability of cellular phenotypes in develo** organisms depends on error-free transmission of epigenetic and genetic information during mitosis....
-
Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma
Cholinergic nerves are involved in tumor progression and dissemination. In contrast to other visceral tissues, cholinergic innervation in the hepatic...
-
Current advancements in B-cell receptor sequencing fast-track the development of synthetic antibodies
Synthetic antibodies (Abs) are a class of engineered proteins designed to mimic the functions of natural Abs. These are produced entirely in vitro,...
-
On Immunological Studies at Sirius University of Science and Technology
AbstractThis short report summarizes the results of recent immunological studies performed at new Sirius University of Science and Technology. The...
-
-
Large-Scale Gene Expression in Monogenic and Complex Genetic Diseases
This chapter will focus on large-scale gene expression in monogenic and complex genetic diseases with an emphasis on immunological diseases....