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Effect of ovarian stimulation by different gonadotrophin treatments on in vivo and in vitro reproductive efficiency of rabbit does under high ambient temperature
Non-lactating multiparous NZW rabbit does ( n = 227) were used in two experiments. In the 1st experiment ( n = 87), does were i.m. injected with 0.1-ml...
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Placentation in Equids
This chapter focuses on the early stages of placental development in horses and their relatives in the genus Equus and highlights unique features of...
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Vitamin D3 reduces the symptoms of ovarian hyperstimulation syndrome in mice and inhibits the release of granulosa cell angiogenic factor through pentraxin 3
It has been reported that the effective inhibition of vascular endothelial growth factor (VEGF) can prevent the progression of ovarian...
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Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility
Chemotherapeutic drugs can cause reproductive damage by affecting sperm quality and other aspects of male fertility. Stem cells are thought to...
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WNT and NOTCH signaling in human trophoblast development and differentiation
Correct development of the human placenta and its differentiated epithelial cells, syncytial trophoblasts (STBs) and extravillous trophoblasts...
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Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation
BackgroundEpigenetic reprogramming is involved in luteinizing hormone (LH)-induced ovulation; however, the underlying mechanisms are largely unknown.
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FURIN and placental syncytialisation: a cautionary tale
FURIN is a pro-protein convertase previously shown to be important for placental syncytialisation (Zhou et al. [
1 ]), a process of cell fusion whereby...
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Repeated controlled ovarian stimulation-induced ovarian and uterine damage in mice through the PI3K/AKT signaling pathway
The effects of repeated controlled ovarian stimulation (COS) on the female reproductive system are still controversial. This study investigated the...
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A burst of genomic innovation at the origin of placental mammals mediated embryo implantation
The origin of embryo implantation in mammals ~148 million years ago was a dramatic shift in reproductive strategy, yet the molecular changes that...
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Induced Pluripotent Stem Cells as a Possible Approach for Exploring the Pathophysiology of Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine condition among women with pleiotropic sequelae possessing reproductive, metabolic,...
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The role of BMP4 signaling in trophoblast emergence from pluripotency
The Bone Morphogenetic Protein (BMP) signaling pathway has established roles in early embryonic morphogenesis, particularly in the epiblast. More...
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In vitro effect of granulocyte–macrophage colony-stimulating factor (GM-CSF) on the expression of genes related to sperm motility and energy metabolism and intracytoplasmic sperm injection outcomes in obstructive azoospermic patients
BackgroundThe presence of granulocyte–macrophage colony-stimulating factor (GM-CSF) and its receptor in various testicular cells and spermatozoa...
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Autophagy-related 7 protein-dependent autophagy mediates resveratrol-caused upregulation of mitochondrial biogenesis and steroidogenesis in aged Leydig cell
BackgroundMitochondrial dysfunction may contribute to decreased testosterone synthesis in aged Leydig cells. Resveratrol (RSV) as an antioxidant has...
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Status of visfatin in female reproductive function under normal and pathological conditions: a mini review
Adipokines are now well-known to regulate reproduction. Visfatin is an adipokine expressed in the hypothalamus, pituitary, ovary, uterus, and...
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Histological and Transcriptomic Insights into the Ovary Development of Hemibarbus labeo Injected with Spawn-Inducing Hormones
Naturally, the ovaries of many farmed fish can only develop to stage IV (mainly including stage IV oocytes, known as full-grown postvitellogenic...
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Structural basis of the subcortical maternal complex and its implications in reproductive disorders
The subcortical maternal complex (SCMC) plays a crucial role in early embryonic development. Malfunction of SCMC leads to reproductive diseases in...
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Long noncoding RNAs and mRNAs profiling in ovary during laying and broodiness in Taihe Black-Bone Silky Fowls (Gallus gallus Domesticus Brisson)
BackgroundBroodiness significantly impacts poultry egg production, particularly notable in specific breeds such as the black-boned Silky,...
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Competence for neural crest induction is controlled by hydrostatic pressure through Yap
Embryonic induction is a key mechanism in development that corresponds to an interaction between a signalling and a responding tissue, causing a...
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Transgenerational inheritance of adrenal steroidogenesis inhibition induced by prenatal dexamethasone exposure and its intrauterine mechanism
BackgroundAdrenal gland is the synthesis and secretion organ of glucocorticoid, which is crucial to fetal development and postnatal fate. Recently,...
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17α-estradiol does not adversely affect sperm parameters or fertility in male mice: implications for reproduction-longevity trade-offs
17α-estradiol (17α-E2) is referred to as a nonfeminizing estrogen that was recently found to extend healthspan and lifespan in male, but not female,...
