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Human Red Blood Cell (RBC) Blood Groups System
Understanding of the blood group system of human gives benefits in transplantation and transfusion medicine. Karl Landsteiner received Noble Prize in...
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Human Blood Serum Counteracts EGFR/HER2-Targeted Drug Lapatinib Impact on Squamous Carcinoma SK-BR-3 Cell Growth and Gene Expression
AbstractLapatinib is a targeted therapeutic inhibiting HER2 and EGFR proteins. It is used for the therapy of HER2-positive breast cancer, although...
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Association between human blood metabolome and the risk of hypertension
Hypertension, commonly referred to as high blood pressure, is a chronic medical condition characterized by persistently elevated blood pressure...
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Measuring human cerebral blood flow and brain function with fiber-based speckle contrast optical spectroscopy system
Cerebral blood flow (CBF) is crucial for brain health. Speckle contrast optical spectroscopy (SCOS) is a technique that has been recently developed...
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Human umbilical cord blood mononuclear cells transplantation for perinatal brain injury
Perinatal brain injury is a leading cause of death and disability in children. Hypoxic-ischemic encephalopathy in full term infants, and white matter...
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Genome–microbiome interplay provides insight into the determinants of the human blood metabolome
Variation in the blood metabolome is intimately related to human health. However, few details are known about the interplay between genetics and the...
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Peptide Derivatives of Human and Rabbit Cathelicidin Reduce Inflammatory Cytokines in Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis Patients
Peptides, as therapeutic agents, can mimic the actions of molecules involved in inflammatory disorders. Antimicrobial peptides (AMPs), generated by...
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In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors
Dendritic cells (DCs) are professional antigen-presenting cells controlling the activation of T cells and thus regulating adaptive immune response...
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Immune profiling of age and adjuvant-specific activation of human blood mononuclear cells in vitro
Vaccination reduces morbidity and mortality due to infections, but efficacy may be limited due to distinct immunogenicity at the extremes of age....
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Blood Coagulation as Coagulation Dysregulation
Prior to human transplantation application, clarification and elucidation of the pig organ compatibility with the human host thromboregulation system...
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Characterization of P2X7 Receptors in Human Blood Cells
P2X7 receptors are expressed in different circulating immune cells. Depending on the cell in which they are expressed, their function could vary from...
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Cellular Blood Flow Modeling with HemoCell
Many of the intriguing properties of blood originate from its cellular nature. Bulk effects, such as viscosity, depend on the local shear rates and...
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Reprogramming of human peripheral blood mononuclear cells into induced mesenchymal stromal cells using non-integrating vectors
Mesenchymal stromal cells (MSCs) have great value in cell therapies. The MSC therapies have many challenges due to its inconsistent potency and...
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Pulmonary embolism and 529 human blood metabolites: genetic correlation and two-sample Mendelian randomization study
BackgroundThe incidence of pulmonary embolism complications in the literature ranges from 10 to 50%, with a 0.5–10% risk of fatal pulmonary embolism....
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Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging
BackgroundVascular aging is an important pathophysiological basis for the senescence of various organs and systems in the human body, and it is a...
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Human T-lymphotropic virus 2 (HTLV-2) prevalence of blood donors in the state of Pará, Brazil
IntroductionThe present study had the objective to describe the molecular prevalence and epidemiological aspects of the human T-lymphotropic virus 2...
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Blood-brain barrier disruption defines the extracellular metabolome of live human high-grade gliomas
The extracellular microenvironment modulates glioma behaviour. It remains unknown if blood-brain barrier disruption merely reflects or functionally...
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Diurnal and circadian rhythmicity of the human blood transcriptome overlaps with organ- and tissue-specific expression of a non-human primate
BackgroundTwenty-four-hour rhythmicity in mammalian tissues and organs is driven by local circadian oscillators, systemic factors, the central...
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Non-ABO Blood Group Systems
After the ABO blood group discovery, Karl Landsteiner and his colleagues further discovered additional markers of blood groups of MN and P, and a...
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The effects of lithium on human red blood cells studied using optical spectroscopy and laser trap
Lithium has been the treatment of choice for patients with bipolar disorder . However, lithium overdose happens more frequently since it has a very...
